Dupuytrens Disease:: A Scientific Review offers consolidated, up-to-date coverage of both the basic normal (nonpathologic) science and cutting-edge science of this progressive disorder. Drs. Lawrence C. Hurst, Marie A. Badalamente, and David Edward Komatsu break down the complex topic of Dupuytren’s contracture into its basic scientific components. Hand surgeons, plastic surgeons, and orthopaedic surgeons will find this unique, concise title to be especially helpful in their practices.
1. Incidence and prevalence of Dupuytren’s disease 2. Epidemiology and risk factors in Dupuytrens disease 3. Anatomy and pathoanatomy in Dupuytrens disease 4. Genetics of Dupuytren’s disease 5. Cells of Dupuytren’s disease 6. Growth factors, hormones, cytokines, and free radicals in Dupuytren’s disease 7. MicroRNAs in Dupuytrens disease 8. Signaling pathways in Dupuytren’s disease 9. Collagen and collagen synthesis in Dupuytren’s disease 10. Collagenase 11. Extracellular matrix in Dupuytren’s disease 12. Developing new therapeutics for Dupuytren’s disease
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