Dupuytrens Disease:: A Scientific Review offers consolidated, up-to-date coverage of both the basic normal (nonpathologic) science and cutting-edge science of this progressive disorder. Drs. Lawrence C. Hurst, Marie A. Badalamente, and David Edward Komatsu break down the complex topic of Dupuytrens contracture into its basic scientific components. Hand surgeons, plastic surgeons, and orthopaedic surgeons will find this unique, concise title to be especially helpful in their practices.
1. Prevalence of Dupuytrens disease 2. Epidemiology of Dupuytrens disease 3. Anatomy and pathoanatomy of Dupuytrens disease 4. Normal genetics and the genetic abnormalities associated with Dupuytrens disease 5. Cells of normal fascia and cells of Dupuytrens disease 6. Growth factors; cytokines; free radicals in healthy fascia and Dupuytrens disease 7. Normal microRNA and abnormal microRNA findings seen with Dupuytrens disease 8. Collagen and collagen synthesis in healthy fascia and Dupuytrens disease 9. Collagenases and collagenase use in Dupuytrens Disease 10. Extra cellular matrix in healthy fascia and Dupuytrens disease 11. Potential therapies suggested by Dupuytrens science 12. Conclusion -Key Points Summary
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