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Hematology Online

PIN Code and User Guide to Continually Updated Online Reference

9780443066702
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Description
The fourth edition of this leading text reflects the new direction and growth of the field of haematology as an academic and clinical discipline. Edited and written by practitioners who are the leaders of the field, the book covers both the basic scientific foundations of haematology and its clinical aspects. It provides practitioners with the most comprehensive, authoritative, up-to-date information in haematology. The table of contents has been thoroughly revised with many new chapters added, reflecting the rapidly changing nature of the molecular and cellular areas of the specialty. This definitive resource is the one comprehensive book needed by every practicing haematologist.
Product Details
Churchill Livingstone
33023
9780443066702
9780443066702

Data sheet

Publication date
2005
Issue number
4
Weight (g)
91
  • Part I. Molecular and Cellular Basis of Hematology 

    Chapter 1 Anatomy and Physiology of the Gene
    Chapter 2 Genomic Approaches to the Study of Hematologic Science NEW
    Chapter 3 Protein Synthesis, Processing, and Degradation REORGANIZED
    Chapter 4 Protein Architecture: Relationship of Form and Function
    Chapter 5 Regulation of Cellular Response NEW
    Chapter 6 Cell Adhesion
    Chapter 7 Control of Cell Division
    Chapter 8 Cell Death NEW
    Chapter 9 Consequences of Genetic Diversity to Hematologic Disease and Treatment NEW



    Part II. Immunologic Basis of Hematology 

    Chapter 10 B-Cell Development
    Chapter 11 T-Cell and NK-Cell Immunity REORGANIZED
    Chapter 12 Dendritic Cell Biology NEW
    Chapter 13 Regulation of Lymphocyte Activation
    Chapter 14 Lymphocyte Trafficking NEW
    Chapter 15 Tolerance and Autoimmunity



    Part III. Biology of Stem Cells and Disorders of Hematopoiesis

    Chapter 16 Stem Cell Model of Hematopoiesis
    Chapter 17 Anatomy and Physiology of Hematopoiesis
    Chapter 18 Humeral Regulation of Hematopoiesis NEW
    Chapter 19 Biology of Erythroppoiesis, Erythroid Differentiation, and Maturation
    Chapter 20 Granulopoiesis and Monocytopoiesis
    Chapter 21 Thrombocytopoiesis
    Chapter 22 Defects in Platelet Production NEW
    Chapter 23 Inherited Forms of Bone Marrow Failure
    Chapter 24 Aplastic Anemia
    Chapter 25 Paroxysmal Nocturnal Hemoglobinuria
    Chapter 26 Pure Red Cell Aplasia



    Part IV. Red Blood Cells

    Chapter 27 Pathobiology of the Human Erythrocyte and Its Hemoglobins
    Chapter 28 Approach to the Adult and Child with Anemia
    Chapter 29 Anemia of Chronic Diseases
    Chapter 30 Disorders of Iron Metabolism: Iron Deficiency and Overload
    Chapter 31 Heme Biosynthesis and Its Disorders: Porphyrias and Sideroblastic Anemias
    Chapter 32 Megablastic Anemias
    Chapter 33 Thalassemia Syndromes
    Chapter 34 Pathology of Sickle Cell Disease
    Chapter 35 Clinical Manifestations and Treatment of Sickle Cell Disease NEW
    Chapter 36 Hemoglobin Variants Associated with Hemolytic Anemia, Altered Oxygen Affinity, and Methemoglobinemias
    Chapter 37 Red Cell Enzymopathies
    Chapter 38 Red Cell Membrane Disorders
    Chapter 39 Autoimmune Hemolytic Anemias
    Chapter 40 Extrinsic Nonimmune Hemolytic Anemias 



    Part V. Host Defense and Its Disorders

    Chapter 41 Immunoglobulins and Complement Biology REORGANIZED
    Chapter 42 Normal Phagocyte Structure and Function
    Chapter 43 Eosinophilia, Eosinophil-Associated Diseases, and the Hypereosinophilic Syndrome
    Chapter 44 Disorders of Phagocyte Function and Number
    Chapter 45 Disorders of Lymphocyte Function
    Chapter 46 Histiocytic Disorders
    Chapter 47 Lysosomal Storage Diseases: Perspective and Principles
    Chapter 48 Infectious Mononucleosis and Other Epstein-Barr Virus-Associated Diseases
    Chapter 49 The Spleen and Its Disorders
    Chapter 50 Basophils, Mast Cells, and Systemic Mastocytosis



    Part VI. Hematologic Malignancies

    Chapter 51 Cytogenetics and Neoplasia
    Chapter 52 The Molecular Basis of Neoplasia
    Chapter 53 Pharmacology and Molecular Mechanism of Action or Resistance of Antineoplastic Agents: Current Status and Future Potential
    Chapter 54 Principles of Radiation Oncology for Hematologic Malignancies NEW
    Chapter 55 Clinical Application of Cytokines
    Chapter 56 Biologic Response Modifiers NEW
    Chapter 57 Pathobiology of Acute Myeloid Leukemia
    Chapter 58 Clinical Manifestations of Acute Myeloid Leukemia
    Chapter 59 Therapy for Acute Myeloid Leukemia
    Chapter 60 Acute Myeloid Leukemia in Children
    Chapter 61 Pathobiology of Acute Lymphoblastic Leukemia
    Chapter 62 Clinical Manifestations of Acute Lymphoblastic Leukemia
    Chapter 63 Treatment of Childhood Acute Lymphoblastic Leukemia
    Chapter 64 Acute Lymphoblastic Leukemia in Adults
    Chapter 65 Myelodysplastic Syndrome
    Chapter 66 Polycthemia Vera
    Chapter 67 Chronic Myelogenous Leukemia
    Chapter 68 Agnogenic Myeloid Metaplasia
    Chapter 69 Primary Thrombocythemia
    Chapter 70 Myelodysplastic Syndromes and Myeloproliferative Syndromes in
    Children
    Chapter 71 Pathobiology of Non-Hodgkin Lymphomas
    Chapter 72 Pathology and Histogenesis of Hodgkin Disease
    Chapter 73 Hodgkin Disease: Clinical Manifestations, Staging, and Therapy
    Chapter 74 The Pathologic Basis for the Classification of Non-Hodgkin
    Lymphomas
    Chapter 75 Clinical Manifestations, Staging, and Treatment of Non-Hodgkin
    Lymphoma
    Chapter 76 Malignant Lymphomas in Childhood
    Chapter 77 Chronic Lymphocytic Leukemia
    Chapter 78 Hairy Cell Leukemia
    Chapter 79 Cutaneous T-Cell Lymphomas
    Chapter 80 AIDS-Related Lymphomas
    Chapter 81 Multiple Myeloma and Other Plasma Cell Disorders
    Chapter 82 Amyloidosis
    Chapter 83 Atypical Immune Lymphoproliferations
    Chapter 84 Clinical Approaches to Infections in the Compromised Host
    Chapter 85 Nutritional Support of Patients with Hematologic Malignancies
    Chapter 86 Psychosocial Aspects of Hematologic Disorders
    Chapter 87 Pain Management and Antiemetic Therapy in Hematologic Disorders
    Chapter 88 Palliative Care NEW
    Chapter 89 Indwelling Access Devices
    Chapter 90 Late Complications of Hematologic Disease and Their Therapies NEW



    Part VII. Transplantation

    Chapter 91 Transplant for Bone Marrow Failure and Autoimmune Disorders NEW
    Chapter 92 Hematopoietic Stem Cell Transplantation for Genetic Diseases and
    Immune Deficiencies NEW
    Chapter 93 Results of Allogeneic Stem Cell Transplantation for Malignant
    Disorders
    Chapter 94 Results of Autologous Stem Cell Transplantation for Malignancies
    Chapter 95 Unrelated Donor Stem Cell Transplantation Therapy
    Chapter 96 Placental and Umbilical Cord Blood Transplantation
    Chapter 97 Preparative Regimens for Stem Cell Transplantation
    Chapter 98 Graft-versus-Host Disease and Graft-versus- Leukemia Effect
    Chapter 99 Achievement of Tolerance NEW
    Chapter 100 Graft Engineering to Enhance Engraftment, Reduce Graft-versus-
    Host Disease, and Provide a Graft-versus-Tumor Effect
    Chapter 101 Gene Therapy for Hematologic Disorders
    Chapter 102 Experimental Cell Therapy
    (include NK-, T-, and dendric cells)
    Chapter 103 Complications After Stem Cell Transplantation



    Part VIII. Hemostasis and Thrombosis

    Chapter 104 Megakaryocyte and Platelet Structure
    Chapter 105 The Molecular Basis for Platelet Function
    Chapter 106 The Molecular Basis for Platelet Activation
    Chapter 107 The Blood Vessel Wall
    Chapter 108 Molecular Basis of Blood Coagulation
    Chapter 109 Molecular and Cellular Basis of Fibrinolysis
    Chapter 110 Regulatory Mechanisms in Hemostasis: Natural Anticoagulants
    Chapter 111 Clinical Evaluation of Hemorrhagic Disorders: The Bleeding History
    and Differential Diagnosis of Pupura
    Chapter 112 Laboratory Evaluation of Hemostatic Disorders REORGANIZED
    Chapter 113 Structure, Biology, and Genetics of Factor VIII
    Chapter 114 Biochemistry of Factor IX and Molecular Biology of Hemophilia B
    Chapter 115 Clinical Aspects and Therapy of Hemophilia
    Chapter 116 Inhibitors in Hemophilia
    Chapter 117 Other Clotting Factor Deficiencies
    Chapter 118 Quantitative and Qualitative Disorders of Fibrinogen
    Chapter 119 Structure, Biology, and Genetics of von Willebrand Factor
    Chapter 120 Clinical Aspects of and Therapy for von Willebrand Disease
    Chapter 121 Vitamin K: Metabolism and Disorders
    Chapter 122 Inhibitors of Blood Coagulation
    Chapter 123 Disseminated Intrvascular Coagulation
    Chapter 124 Hemostatic Defects Associated with Dysproteinemias
    Chapter 125 Disorders of Coagulation and Platelets in the Neonate
    Chapter 126 Hypercoagulable States
    Chapter 127 Venous Thromboembolism
    Chapter 128 Arterial Thromboembolism
    Chapter 129 Anticoagulation and Thrombolytic Therapy REORGANIZED
    Chapter 130 Immune Thrombocytopenic Purpura, Neonatal Alloimmune
    Thrombocytopenia, and Posttransfusion Purpura
    Chapter 131 Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic
    Syndrome
    Chapter 132 Thrombocytopenia Due to Platelet Destruction and Hypersplenism
    Chapter 133 Hereditary Disorders of Platelet Function
    Chapter 134 Acquired Disorders of Platelet Function



    Part IX. Transfusion Medicine

    Chapter 135 Human Blood Group Anitgens and Antibodies
    Part 1: Carbohydrate Determinants
    Part 2: Protein Determinants
    Chapter 136 Human Platelet Antigens
    Chapter 137 HLA and Neutrophil Antigen and Antibody Systems
    Chapter 138 Principles of Red Blood Cell Transfusion
    Chapter 139 Principles of Platelet Transfusion Therapy
    Chapter 140 Principles of Neutrophil (Granulocyte) Transfusions
    Chapter 141 Transfusion of Plasma Derivatives: Fresh-Frozen Plasma,
    Cryoprecipitate, Albumin, and Immunoglobulins
    Chapter 142 Intravenous Immunoglobulin NEW
    Chapter 143 Preparation of Plasma-Derived and Recombinant Human Plasma
    Proteins
    Chapter 144 Transfusion Principles for Congenital Coagulation Disorders
    Chapter 145 Hemapheresis and Cellular Therapy NEW
    Chapter 146 Practical Aspects of Stem Cell Collection
    Chapter 147 Transfusion Reactions
    Chapter 148 Transfusion-Transmitted Diseases
    Chapter 149 Transfusion Medicine in Hematopoietic Stem Cell and Solid Organ
    Transplantation



    Part X. Consultative Hematology


    Chapter 150 Hematologic Manifestations of Systemic Disease: Liver and Renal
    Disease REORGANIZED
    Chapter 151 Hematologic Manifestations of Systemic Disease: Infection,
    Chronic Inflammation, and Cancer
    Chapter 152 Hematologic Manifestations of Systemic Disease: HIV Infection
    Chapter 153 Hematologic Problems in the Surgical Patient: Bleeding and Thrombosis
    Chapter 154 Hematologic Aspects of Pregnancy
    Chapter 155 Hematologic Manifestations of Childhood Illness



    Part XI. Special Tests and Procedures


    Chapter 156 Bone Marrow Aspiration and Morphology
    Chapter 157 Automated Analysis of Blood Cells
    Chapter 158 Laboratory Detection of Hemoglobinopathies and Thalassemias
    Chapter 159 Antenatal Diagnosis of Hematologic Disorders
    Chapter 160 Use of Molecular Techniques in the Analysis of Hematologic Diseases
    Chapter 161 Special Imaging Applications in Hematology NEW
    Chapter 162 Coagulation Studies and Their Interpretation NEW
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