Hematology Online

PIN Code and User Guide to Continually Updated Online Reference

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Wydawca: Churchill Livingstone

ISBN: 9780443066702

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Opis

The fourth edition of this leading text reflects the new direction and growth of the field of haematology as an academic and clinical discipline. Edited and written by practitioners who are the leaders of the field, the book covers both the basic scientific foundations of haematology and its clinical aspects. It provides practitioners with the most comprehensive, authoritative, up-to-date information in haematology. The table of contents has been thoroughly revised with many new chapters added, reflecting the rapidly changing nature of the molecular and cellular areas of the specialty. This definitive resource is the one comprehensive book needed by every practicing haematologist.

Szczegóły produktu

Wydawca Churchill Livingstone

Indeks 33023

EAN13 9780443066702

ISBN 9780443066702

Opis

Rok wydania: 2005
Numer wydania: 4
Waga (g): 91

Part I. Molecular and Cellular Basis of Hematology

Chapter 1 Anatomy and Physiology of the Gene
Chapter 2 Genomic Approaches to the Study of Hematologic Science NEW
Chapter 3 Protein Synthesis, Processing, and Degradation REORGANIZED
Chapter 4 Protein Architecture:: Relationship of Form and Function
Chapter 5 Regulation of Cellular Response NEW
Chapter 6 Cell Adhesion
Chapter 7 Control of Cell Division
Chapter 8 Cell Death NEW
Chapter 9 Consequences of Genetic Diversity to Hematologic Disease and Treatment NEW

Part II. Immunologic Basis of Hematology

Chapter 10 B-Cell Development
Chapter 11 T-Cell and NK-Cell Immunity REORGANIZED
Chapter 12 Dendritic Cell Biology NEW
Chapter 13 Regulation of Lymphocyte Activation
Chapter 14 Lymphocyte Trafficking NEW
Chapter 15 Tolerance and Autoimmunity

Part III. Biology of Stem Cells and Disorders of Hematopoiesis

Chapter 16 Stem Cell Model of Hematopoiesis
Chapter 17 Anatomy and Physiology of Hematopoiesis
Chapter 18 Humeral Regulation of Hematopoiesis NEW
Chapter 19 Biology of Erythroppoiesis, Erythroid Differentiation, and Maturation
Chapter 20 Granulopoiesis and Monocytopoiesis
Chapter 21 Thrombocytopoiesis
Chapter 22 Defects in Platelet Production NEW
Chapter 23 Inherited Forms of Bone Marrow Failure
Chapter 24 Aplastic Anemia
Chapter 25 Paroxysmal Nocturnal Hemoglobinuria
Chapter 26 Pure Red Cell Aplasia

Part IV. Red Blood Cells

Chapter 27 Pathobiology of the Human Erythrocyte and Its Hemoglobins
Chapter 28 Approach to the Adult and Child with Anemia
Chapter 29 Anemia of Chronic Diseases
Chapter 30 Disorders of Iron Metabolism:: Iron Deficiency and Overload
Chapter 31 Heme Biosynthesis and Its Disorders:: Porphyrias and Sideroblastic Anemias
Chapter 32 Megablastic Anemias
Chapter 33 Thalassemia Syndromes
Chapter 34 Pathology of Sickle Cell Disease
Chapter 35 Clinical Manifestations and Treatment of Sickle Cell Disease NEW
Chapter 36 Hemoglobin Variants Associated with Hemolytic Anemia, Altered Oxygen Affinity, and Methemoglobinemias
Chapter 37 Red Cell Enzymopathies
Chapter 38 Red Cell Membrane Disorders
Chapter 39 Autoimmune Hemolytic Anemias
Chapter 40 Extrinsic Nonimmune Hemolytic Anemias

Part V. Host Defense and Its Disorders

Chapter 41 Immunoglobulins and Complement Biology REORGANIZED
Chapter 42 Normal Phagocyte Structure and Function
Chapter 43 Eosinophilia, Eosinophil-Associated Diseases, and the Hypereosinophilic Syndrome
Chapter 44 Disorders of Phagocyte Function and Number
Chapter 45 Disorders of Lymphocyte Function
Chapter 46 Histiocytic Disorders
Chapter 47 Lysosomal Storage Diseases:: Perspective and Principles
Chapter 48 Infectious Mononucleosis and Other Epstein-Barr Virus-Associated Diseases
Chapter 49 The Spleen and Its Disorders
Chapter 50 Basophils, Mast Cells, and Systemic Mastocytosis

Part VI. Hematologic Malignancies

Chapter 51 Cytogenetics and Neoplasia
Chapter 52 The Molecular Basis of Neoplasia
Chapter 53 Pharmacology and Molecular Mechanism of Action or Resistance of Antineoplastic Agents:: Current Status and Future Potential
Chapter 54 Principles of Radiation Oncology for Hematologic Malignancies NEW
Chapter 55 Clinical Application of Cytokines
Chapter 56 Biologic Response Modifiers NEW
Chapter 57 Pathobiology of Acute Myeloid Leukemia
Chapter 58 Clinical Manifestations of Acute Myeloid Leukemia
Chapter 59 Therapy for Acute Myeloid Leukemia
Chapter 60 Acute Myeloid Leukemia in Children
Chapter 61 Pathobiology of Acute Lymphoblastic Leukemia
Chapter 62 Clinical Manifestations of Acute Lymphoblastic Leukemia
Chapter 63 Treatment of Childhood Acute Lymphoblastic Leukemia
Chapter 64 Acute Lymphoblastic Leukemia in Adults
Chapter 65 Myelodysplastic Syndrome
Chapter 66 Polycthemia Vera
Chapter 67 Chronic Myelogenous Leukemia
Chapter 68 Agnogenic Myeloid Metaplasia
Chapter 69 Primary Thrombocythemia
Chapter 70 Myelodysplastic Syndromes and Myeloproliferative Syndromes in
Children
Chapter 71 Pathobiology of Non-Hodgkin Lymphomas
Chapter 72 Pathology and Histogenesis of Hodgkin Disease
Chapter 73 Hodgkin Disease:: Clinical Manifestations, Staging, and Therapy
Chapter 74 The Pathologic Basis for the Classification of Non-Hodgkin
Lymphomas
Chapter 75 Clinical Manifestations, Staging, and Treatment of Non-Hodgkin
Lymphoma
Chapter 76 Malignant Lymphomas in Childhood
Chapter 77 Chronic Lymphocytic Leukemia
Chapter 78 Hairy Cell Leukemia
Chapter 79 Cutaneous T-Cell Lymphomas
Chapter 80 AIDS-Related Lymphomas
Chapter 81 Multiple Myeloma and Other Plasma Cell Disorders
Chapter 82 Amyloidosis
Chapter 83 Atypical Immune Lymphoproliferations
Chapter 84 Clinical Approaches to Infections in the Compromised Host
Chapter 85 Nutritional Support of Patients with Hematologic Malignancies
Chapter 86 Psychosocial Aspects of Hematologic Disorders
Chapter 87 Pain Management and Antiemetic Therapy in Hematologic Disorders
Chapter 88 Palliative Care NEW
Chapter 89 Indwelling Access Devices
Chapter 90 Late Complications of Hematologic Disease and Their Therapies NEW

Part VII. Transplantation

Chapter 91 Transplant for Bone Marrow Failure and Autoimmune Disorders NEW
Chapter 92 Hematopoietic Stem Cell Transplantation for Genetic Diseases and
Immune Deficiencies NEW
Chapter 93 Results of Allogeneic Stem Cell Transplantation for Malignant
Disorders
Chapter 94 Results of Autologous Stem Cell Transplantation for Malignancies
Chapter 95 Unrelated Donor Stem Cell Transplantation Therapy
Chapter 96 Placental and Umbilical Cord Blood Transplantation
Chapter 97 Preparative Regimens for Stem Cell Transplantation
Chapter 98 Graft-versus-Host Disease and Graft-versus- Leukemia Effect
Chapter 99 Achievement of Tolerance NEW
Chapter 100 Graft Engineering to Enhance Engraftment, Reduce Graft-versus-
Host Disease, and Provide a Graft-versus-Tumor Effect
Chapter 101 Gene Therapy for Hematologic Disorders
Chapter 102 Experimental Cell Therapy
(include NK-, T-, and dendric cells)
Chapter 103 Complications After Stem Cell Transplantation

Part VIII. Hemostasis and Thrombosis

Chapter 104 Megakaryocyte and Platelet Structure
Chapter 105 The Molecular Basis for Platelet Function
Chapter 106 The Molecular Basis for Platelet Activation
Chapter 107 The Blood Vessel Wall
Chapter 108 Molecular Basis of Blood Coagulation
Chapter 109 Molecular and Cellular Basis of Fibrinolysis
Chapter 110 Regulatory Mechanisms in Hemostasis:: Natural Anticoagulants
Chapter 111 Clinical Evaluation of Hemorrhagic Disorders:: The Bleeding History
and Differential Diagnosis of Pupura
Chapter 112 Laboratory Evaluation of Hemostatic Disorders REORGANIZED
Chapter 113 Structure, Biology, and Genetics of Factor VIII
Chapter 114 Biochemistry of Factor IX and Molecular Biology of Hemophilia B
Chapter 115 Clinical Aspects and Therapy of Hemophilia
Chapter 116 Inhibitors in Hemophilia
Chapter 117 Other Clotting Factor Deficiencies
Chapter 118 Quantitative and Qualitative Disorders of Fibrinogen
Chapter 119 Structure, Biology, and Genetics of von Willebrand Factor
Chapter 120 Clinical Aspects of and Therapy for von Willebrand Disease
Chapter 121 Vitamin K:: Metabolism and Disorders
Chapter 122 Inhibitors of Blood Coagulation
Chapter 123 Disseminated Intrvascular Coagulation
Chapter 124 Hemostatic Defects Associated with Dysproteinemias
Chapter 125 Disorders of Coagulation and Platelets in the Neonate
Chapter 126 Hypercoagulable States
Chapter 127 Venous Thromboembolism
Chapter 128 Arterial Thromboembolism
Chapter 129 Anticoagulation and Thrombolytic Therapy REORGANIZED
Chapter 130 Immune Thrombocytopenic Purpura, Neonatal Alloimmune
Thrombocytopenia, and Posttransfusion Purpura
Chapter 131 Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic
Syndrome
Chapter 132 Thrombocytopenia Due to Platelet Destruction and Hypersplenism
Chapter 133 Hereditary Disorders of Platelet Function
Chapter 134 Acquired Disorders of Platelet Function

Part IX. Transfusion Medicine

Chapter 135 Human Blood Group Anitgens and Antibodies
Part 1:: Carbohydrate Determinants
Part 2:: Protein Determinants
Chapter 136 Human Platelet Antigens
Chapter 137 HLA and Neutrophil Antigen and Antibody Systems
Chapter 138 Principles of Red Blood Cell Transfusion
Chapter 139 Principles of Platelet Transfusion Therapy
Chapter 140 Principles of Neutrophil (Granulocyte) Transfusions
Chapter 141 Transfusion of Plasma Derivatives:: Fresh-Frozen Plasma,
Cryoprecipitate, Albumin, and Immunoglobulins
Chapter 142 Intravenous Immunoglobulin NEW
Chapter 143 Preparation of Plasma-Derived and Recombinant Human Plasma
Proteins
Chapter 144 Transfusion Principles for Congenital Coagulation Disorders
Chapter 145 Hemapheresis and Cellular Therapy NEW
Chapter 146 Practical Aspects of Stem Cell Collection
Chapter 147 Transfusion Reactions
Chapter 148 Transfusion-Transmitted Diseases
Chapter 149 Transfusion Medicine in Hematopoietic Stem Cell and Solid Organ
Transplantation

Part X. Consultative Hematology

Chapter 150 Hematologic Manifestations of Systemic Disease:: Liver and Renal
Disease REORGANIZED
Chapter 151 Hematologic Manifestations of Systemic Disease:: Infection,
Chronic Inflammation, and Cancer
Chapter 152 Hematologic Manifestations of Systemic Disease:: HIV Infection
Chapter 153 Hematologic Problems in the Surgical Patient:: Bleeding and Thrombosis
Chapter 154 Hematologic Aspects of Pregnancy
Chapter 155 Hematologic Manifestations of Childhood Illness

Part XI. Special Tests and Procedures

Chapter 156 Bone Marrow Aspiration and Morphology
Chapter 157 Automated Analysis of Blood Cells
Chapter 158 Laboratory Detection of Hemoglobinopathies and Thalassemias
Chapter 159 Antenatal Diagnosis of Hematologic Disorders
Chapter 160 Use of Molecular Techniques in the Analysis of Hematologic Diseases
Chapter 161 Special Imaging Applications in Hematology NEW
Chapter 162 Coagulation Studies and Their Interpretation NEW