In this issue of Cardiac Electrophysiology Clinics, guest editors Drs. Luigi Di Biase and Fengwei Zou bring their considerable expertise to the topic of Pulsed Field Ablation. Pulsed Field Ablation (PFA) is a promising and evolving technology in the field of cardiac electrophysiology, with ongoing research exploring its safety and efficacy. In this issue, top experts discuss lesion characteristics of PFA; tissue selectivity of PFA; pulmonary vein isolation with PFA; and much more.