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Introduction to the Pharmaceutical Sciences

9780781744782
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Description

This unique textbook provides an introductory, yet comprehensive overview of the pharmaceutical sciences. It is the first text of its kind to pursue an interdisciplinary approach in this area of study. Readers are introduced to basic concepts related to the specific disciplines in the pharmaceutical sciences, including pharmacology, pharmaceutics, pharmacokinetics, and medicinal chemistry. In an easy-to-read writing style, the book provides readers with up-to-date information on pharmacogenomics and includes comprehensive coverage of industrial drug development and regulatory approval processes.

Each chapter includes chapter outlines and critical-thinking exercises, as well as numerous tables and graphs. More than 160 illustrations complement the text.

Product Details
38295
9780781744782
9780781744782

Data sheet

Publication date
2006
Issue number
1
Cover
hard cover
Pages count
416
Dimensions (mm)
178 x 254
Weight (g)
862
  • 1. Introduction 1

    Section I:: Basic Principles 9
    2. Ionization of Drugs 11
    3. Solubility and Lipophilicity 27
    4. Rates of Pharmaceutical Processes 43
    5. Membranes and Tissues 61

    Section II:: Drug Structure and Design 75
    6. Drugs and Their Targets 77
    7. Drug Discovery and Optimization 93
    8. Transport Across Biological Barriers 109

    Section III:: Drug Delivery 131
    9. Drug Absorption 133
    10. Drug Delivery Systems 147

    Section IV:: Drug Disposition 161
    11. Drug Distribution 163
    12. Drug Excretion 179
    13. Drug Metabolism 193
    14. Plasma Concentration-Time Curves 213

    Section V:: Drug Action 227
    15. Ligands and Receptors 229
    16. Mechanisms of Drug Action 255
    17. Dose-Response Relationships 277

    Section VI:: Drug Therapy 291
    18. Therapeutic Variability 293
    19. Drug Interactions 307
    20. Pharmacogenomics 321

    Section VII:: Special Topics 341
    21. Biopharmaceuticals 343
    22. Drug Discovery, Development, and Approval 369
    Index 387
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