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Introduction to the Pharmaceutical Sciences
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This unique textbook provides an introductory, yet comprehensive overview of the pharmaceutical sciences. It is the first text of its kind to pursue an interdisciplinary approach in this area of study. Readers are introduced to basic concepts related to the specific disciplines in the pharmaceutical sciences, including pharmacology, pharmaceutics, pharmacokinetics, and medicinal chemistry. In an easy-to-read writing style, the book provides readers with up-to-date information on pharmacogenomics and includes comprehensive coverage of industrial drug development and regulatory approval processes.
Each chapter includes chapter outlines and critical-thinking exercises, as well as numerous tables and graphs. More than 160 illustrations complement the text.
Data sheet
- Publication date
- 2006
- Issue number
- 1
- Cover
- hard cover
- Pages count
- 416
- Dimensions (mm)
- 178 x 254
- Weight (g)
- 862
- 1. Introduction 1
Section I:: Basic Principles 9
2. Ionization of Drugs 11
3. Solubility and Lipophilicity 27
4. Rates of Pharmaceutical Processes 43
5. Membranes and Tissues 61
Section II:: Drug Structure and Design 75
6. Drugs and Their Targets 77
7. Drug Discovery and Optimization 93
8. Transport Across Biological Barriers 109
Section III:: Drug Delivery 131
9. Drug Absorption 133
10. Drug Delivery Systems 147
Section IV:: Drug Disposition 161
11. Drug Distribution 163
12. Drug Excretion 179
13. Drug Metabolism 193
14. Plasma Concentration-Time Curves 213
Section V:: Drug Action 227
15. Ligands and Receptors 229
16. Mechanisms of Drug Action 255
17. Dose-Response Relationships 277
Section VI:: Drug Therapy 291
18. Therapeutic Variability 293
19. Drug Interactions 307
20. Pharmacogenomics 321
Section VII:: Special Topics 341
21. Biopharmaceuticals 343
22. Drug Discovery, Development, and Approval 369
Index 387
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