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Fragment-Based Drug Discovery

Fragment-Based Drug Discovery

9781849739085
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Description
Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written from a Chemists perspective and comprehensively assesses the impact of fragment-based drug discovery on a wide variety of areas of medicinal chemistry. It will prove to be an invaluable resource for medicinal chemists working in academia and industry, as well as anyone interested in novel drug discovery techniques.
Product Details
Royal Society for Chemistry
77338
9781849739085
9781849739085

Data sheet

Publication date
2015
Issue number
1
Cover
hard cover
Pages count
314
Dimensions (mm)
156.00 x 234.00
Weight (g)
623
  • Different flavours of Fragments; Advances in SPR Technology; Applications of NMR in Fragment-Based Drug Discovery; Issues around Fragments as an Approach, including a Computational/in silico Perspectives on Fragment-Based Drug Discovery; Fragment-Based Drug Discovery of Kinase Inhibitors; Fragment-Based Discovery of Antibacterials; Strategies for Fragment-Based Lead Generation; Fragment-Based Approaches to Epigenetic Targets; Application of Fragment-Based Drug Discovery to GPCRs; Fragment-Based Drug Discovery applied to Protein-Protein Interactions; Probing Difficult Targets
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