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Neonatal and Pediatric Pharmacology
Therapeutic Principles in Practice
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Written by experts at the forefront of current research and clinical practice, this volume provides evidence-based guidelines for safe, effective, and rational drug therapy in newborns, children, and adolescents. Coverage includes specific recommendations for all major drug classes and diseases, a detailed section on drugs and the newborn, and chapters on specific treatment settings such as the pediatric intensive care unit and emergency room. Also included are chapters on adverse effects and interactions and state-of-the-art discussions on pharmacokinetics, pharmacodynamics, pharmacogenetics, drug development, and clinical drug trials in infants and children. Appendices include a neonatal formulary and a pediatric formulary.
Data sheet
- Publication date
- 2004
- Issue number
- 3
- Cover
- hard cover
- Pages count
- 880
- Dimensions (mm)
- 216 x 279
- Weight (g)
- 2377
I. GENERAL PRINCIPLES
- INTRODUCTION AND HISTORICAL PERSPECTIVES
Sumner J. Yaffe and Jacob V. Aranda
- CLINICAL PHARMACOKINETICS IN INFANTS AND CHILDREN
Edmund V. Capparelli
- DRUG ACTION AND THERAPY IN THE INFANT AND CHILD
Ralph E. Kauffman
- DRUG METABOLISM AND DISPOSITION IN INFANTS AND CHILDREN
Anders Rane
- PHARMACOGENETICS, PHARMACOGENOMICS, AND PHARMACOPROTEOMICS
J. Steven Leeder
- COMPLIANCE WITH PEDIATRIC MEDICATION REGIMENS
Hakan Ergun and Daniel A.C. Frattarelli
- CLINICAL TRIALS INVOLVING CHILDREN:: HISTORY, RATIONALE, AND TECHNICAL CONSIDERATIONS
Steven Hirschfeld
- ETHICS OF DRUG RESEARCH IN PEDIATRIC POPULATIONS
Sanford N. Cohen and Bruce L. Russell
- THERAPEUTIC DRUG MONITORING
Alexander A. Vinks and Philip D. Walson
- DRUG FORMULATIONS
Milap C. Nahata
II. DRUGS AND THE NEWBORN
- OVERVIEW OF DRUGS IN PREGNANCY
Donald R. Mattison and John F. Young
- PLACENTAL TRANSFER OF DRUGS
Rada Boskovic and Gideon Koren
- PERINATAL ORIGINS OF ADULT DEFECTS IN DRUG METABOLISM
Bernard H. Shapiro
- PRINCIPLES OF NEONATAL PHARMACOLOGY
Jeffrey L. Blumer and Michael D. Reed
- RENAL FUNCTION AND EXCRETION OF DRUGS IN THE NEWBORN
John van den Anker
- THE EXCRETION OF DRUGS AND CHEMICALS IN HUMAN MILK
Cheston M. Berlin
- DRUGS FOR HYPERBILIRUBINEMIA
David K. Stevenson, Susan R. Hintz, Ronald J. Wong, and Hendrik J. Vremen
- DRUGS AND LUNG DEVELOPMENT
Alan H. Jobe
- DRUGS IN NEONATAL APNEA
J.M. Lopez and Jacob V. Aranda
- DRUGS AND PERINATAL BRAIN INJURY
Maria Delivoria Papadopoulos, Agustin Legido, and Om Prakash Mishra
- ANTIRETROVIRAL PHARMACOLOGY IN PREGNANT WOMEN AND NEWBORNS
Mark MirochnickIII. DRUGS IN SPECIAL POPULATIONS AND SETTINGS
- THERAPEUTIC APPLICATIONS IN PEDIATRIC INTENSIVE CARE
Mary Lieh-Lai and Ashok Sarnaik
- DRUG THERAPY IN THE PEDIATRIC EMERGENCY DEPARTMENT
Shannon Manzi and Michael Shannon
- DRUG THERAPY IN THE ADOLESCENT
Ian M. Paul and Richard L. Levine
- TOPICAL MEDICATIONS
Fasahat H. Hamzavi and George J. Murakawa
- OPHTHALMOLOGIC DRUGS IN INFANTS AND CHILDREN
John D. RoartyIV. SPECIFIC DRUGS
- SULFONAMIDES AND QUINOLONES
Jacob V. Aranda, et al.
- PENICILLIN, BETA-LACTAM INHIBITORS, CEPHALOPSPORINS
Sumathi Nambiar and William J. Rodriguez
- AMINOGLYCOSIDES AND GLYCOPEPTIDES
Matthijs de Hoog and John van den Anker
- MACROLIDES, CHLORAMPHENICOL, AND TETRACYCLINES
Basim Asmar
- ANTHELMINTHIC DRUGS IN CHILDREN
George C.F. Hsieh, Vincent C. Fan, and Peter J. Hotez
- ANTI-TUBERCULOSIS DRUGS
Alexander O. Tuazon
- ANTIFUNGAL AGENTS
William J. Steinbach and John R. Perfect
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