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Principles of Pharmacology

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Principles of Pharmacology
Principles of Pharmacology

Principles of Pharmacology

The Pathophysiologic Basis of Drug Therapy

9780781783552
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Description

This primary textbook for a first course in pharmacology offers an integrated, systems-based, and mechanism-based approach to understanding drug therapy. Each chapter focuses on a target organ system, begins with a clinical case, and incorporates cell biology, biochemistry, physiology, and pathophysiology to explain how and why different drug classes are effective for diseases in that organ system.

Over 400 two-color illustrations show molecular, cellular, biochemical, and pathophysiologic processes underlying diseases and depict targets of drug therapy. Each Second Edition chapter includes a drug summary table presenting mechanism, clinical applications, adverse effects, contraindications, and therapeutic considerations. New chapters explain how drugs produce adverse effects and describe the life cycle of drug development.

The fully searchable online text and an image bank are available on thePoint.

Product Details
Lippincott Williams & Wilkins
40871
9780781783552
9780781783552

Data sheet

Publication date
2007
Issue number
2
Cover
paperback
Pages count
985
Dimensions (mm)
213 x 276
Weight (g)
2268

  • FUNDAMENTAL PRINCIPLES OF PHARMACOLOGY
    Drug-Receptor Interactions
    Pharmacodynamics
    Pharmacokinetics
    Drug Metabolism
    Drug Toxicity

    PRINCIPLES OF NEUROPHARMACOLOGY

    Fundamental Principles of Neuropharmacology
    Principles of Cellular Excitability and Electrochemical Transmission
    Principles of Nervous System Physiology and Pharmacology

    Principles of Autonomic and Peripheral Nervous System Pharmacology
    Cholinergic Pharmacology
    Adrenergic Pharmacology
    Local Anesthetic Pharmacology

    Principles of Central Nervous System Pharmacology
    Pharmacology of GABAergic and Glutamatergic Neurotransmission
    Pharmacology of Dopaminergic Neurotransmission
    Pharmacology of Central Adrenergic and Serotonergic Neurotransmission
    Pharmacology of Abnormal Electrical Neurotransmission in the Central Nervous System
    General Anesthetic Pharmacology
    Pharmacology of Analgesia
    Pharmacology of Drug and Alcohol Abuse and Dependence

    PRINCIPLES OF CARDIOVASCULAR PHARMACOLOGY
    Pharmacology of Cardiac Rhythm
    Pharmacology of Cardiac Contractility
    Pharmacology of Volume Regulation
    Pharmacology of Vascular Tone
    Pharmacology of Hemostasis and Thrombosis
    Pharmacology of Cholesterol and Lipoprotein Metabolism
    Integrative Cardiovascular Pharmacology:: Hypertension, Ischemic Heart Disease, and Heart Failure

    PRINCIPLES OF ENDOCRINE PHARMACOLOGY
    Pharmacology of the Hypothalamus and Pituitary Gland
    Pharmacology of the Thyroid Gland
    Pharmacology of the Adrenal Cortex
    Pharmacology of Reproduction
    Pharmacology of the Endocrine Pancreas
    Pharmacology of Bone Mineral Homeostasis

    PRINCIPLES OF CHEMOTHERAPY
    Principles of Antimicrobial and Antineoplastic Pharmacology
    Pharmacology of Bacterial Infections:: Central Dogma Processes
    Pharmacology of Bacterial Infections:: Cell Wall Synthesis
    Pharmacology of Fungal Infections
    Pharmacology of Parasitic Infections
    Pharmacology of Viral Infections
    Pharmacology of Cancer:: DNA Synthesis, Stability, and Maintenance
    Pharmacology of Cancer:: Signal Transduction
    Principles of Combination Chemotherapy

    PRINCIPLES OF INFLAMMATION AND IMMUNE PHARMACOLOGY
    Principles of Inflammation and the Immune System
    Pharmacology of Eicosanoids
    Histamine Pharmacology
    Pharmacology of Hematopoietic and Immune Cell Stimulation
    Pharmacology of Immunosuppression
    Integrative Inflammation Pharmacology:: Peptic Ulcer Disease
    Integrative Inflammation Pharmacology:: Asthma
    Integrative Inflammation Pharmacology:: Gout

    FUNDAMENTALS OF DRUG DEVELOPMENT AND REGULATION
    Drug Discovery and Preclinical Development
    Clinical Drug Evaluation and Regulatory Approval
    Detection and Management of Adverse Events in Marketed Drugs

    POISONING BY DRUGS AND ENVIRONMENTAL TOXINS

    FRONTIERS IN PHARMACOLOGY
    Pharmacogenomics
    Protein-Based and Gene Therapies
    Drug Delivery Modalities

See next edition:

Principles of Pharmacology
Principles of Pharmacology
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