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Therapy for Ocular Angiogenesis

Therapy for Ocular Angiogenesis

Principles and Practice

9781605476407
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Description

Ocular angiogenesis, or the abnormal growth of blood vessels in the eye, is the cause of major neovascular eye diseases. In addition, retinal and choroidal neovascularization are the major causes of vision loss in this country. With the new era of anti-angiogenic therapies already in practice, ophthalmologists have started treating many ocular diseases including macular degeneration, diabetic retinopathy, and retinal vascular occlusion using anti-angiogenic drugs.

Therapy for Ocular Angiogenesis:: Principles and Practice covers the basic pathophysiology of ocular angiogenesis and strategies for inhibition. The authors discuss the Principles of anti-angiogenic therapy, pre-clinical studies, future drugs on the horizon, drug delivery, and the Practice of the therapy in many ocular diseases. Vision researchers in both academia and industry, as well as clinician scientists, have contributed chapters on different aspects of the angiogenic process, and clinical strategies to fight it. The book also includes chapters that deal with diabetic macular edema, and various therapeutic options for this condition.

A companion website includes the fully searchable text and an image bank.

Product Details
LWW
48195
9781605476407
9781605476407

Data sheet

Publication date
2010
Issue number
1
Cover
hard cover
Pages count
464
Dimensions (mm)
213 x 276
Weight (g)
1202

  • I:: PRINCIPLES

    1:: Tumor Angiogenesis:: Concept
    Judah Folkman (Reproduction of the Hellen Keller Foundation Lecture 2006)

    2:: Retinal Neovascularization:: Pathophysiology
    Robert Frank

    3:: Choroidal Neovascularization:: Pathophysiology
    J. Ambati

    4:: VEGF the Major Player
    Patricia DAmore

    5:: IFG-1 in Angiogenesis
    Lois Smith

    6:: Is It All the VEGF? Other Factors
    John Penn

    7:: Proteinases and Integrins
    Alexander Ljubimov and Arup Das

    8:: Endogenous Inhibitors
    David Hinton

    9:: Macular Edema:: Molecular Mechanisms
    Arup Das

    II:: PRACTICE

    1:: Anti-VEGF Therapies in ARMD in Practice
    Jeff Heier

    2:: Novel Anti-VEGF Drugs in ARMD Currently in Trials
    Quan Nguyen

    3:: Safety of Anti-VEGF Drugs
    David Boyer and Thomas Friberg

    4:: Pharmacokinetics of Anti-VEGF Drugs
    Karl Casky

    5:: Anti-VEGF Therapies of Retinal Neovascularization
    Allen Ho

    6:: Anti-VEGF Therapies in Diabetic Macular Edema
    Lloyd Aiello

    7:: Steroids in ARMD and Macular Edema
    Jennifer Lim

    8:: Anti-VEGF Therapies in ROP
    Antonio Capone

    9:: Pharmacotherapy in Retinal Vein Occlusions
    Michael Ip

    10:: Intravitreal Injection:: Technique and Complications
    Elias Reichel

    11:: Role of OCT in Management of ARMD and Macular Edema
    Srinivas Sadda

    12:: Role of Laser in the Era of Pharmacotherapy
    Thomas Friberg

    13:: PDT:: Is It an Option?
    Albert Augustin

    14:: Combination Therapy:: Future
    Richard Spaide

    15:: Gene Therapy in Ocular Angiogenesis
    Rajendra Kumar-Singh

    16:: Stem Cell Therapy
    Maria Grant

    17:: Drug Delivery in Posterior Segment:: Challenges
    Prithvi Mruthyunjaya and Glenn Jaffe

    18:: Corneal Neovascularization
    Bala Ambati

    19:: Neovascular Glaucoma
    James Tsai

    20:: Financial Impact of Anti-Angiogenic Therapy
    George Williams

    21:: Future of Anti-Angiogenic Therapy
    Anthony Adamis

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