This book summarises current studies which involve receptors and ligands in neurological disorders. The advance in the study of receptors in general enables investigators to explore the mechanism of action of psychotropic drugs and to minimise their side effects. It will lead to the study of molecular events and an understanding of the nature and cause of the various diseases and to more accurate diagnoses which may give more effective therapeutic treatments. Each chapter is written by experts in the field and the volume has been carefully edited to ensure its usefulness to pharmacologists, neurologists and neuroscieentists.
Preface; Introduction; 1. Cnolinergic neurons in Huntingtons disease K. G. Lloyd and C. J. Carter; 2. GABA deficiency in Humtingtons disease Thomas L. Perry; 3. The role of cental dopamine in movement disorders Menek Goldstein and Emanual Meller; 4. Tardive dyskinesia - a historical review Caroline M. Tanner and Harold L. Klawans; 5. Gilles de la tourette syndrome Jack W. Schweitzer and Arnold J. Friedhoff; 6. Aluminium and Alzheimers disease D. R. Crapper McLachlan; 7. Cortical neurotransmitter receptors:: distribution and involvement in Alzheimers disease E. K. Parry and J. M. Candy; 8. Neurotransmitter receptors in normal human aging and Alzheimers disease David G. Morgan, Patrick C. May and Caleb E. Finch; 9. Acetylocholine receptor in myasthenia gravis R. J. Boegman and K. K. Wan; 10. Receptor binding in the kindling model of epilepsy W. M. Burnham; 11. Imagining of regional celebral metabolism and blood flow in epilepsy George J. Siegel, Bassel Abou-Khalil and J. Chris Sackellares; 12. A review of the attentional deficit disorder of chilhood Lisa A. Raskin, Sally E. Shaywitz, Bennett A. Shaywitz, George M. Anderson, James F. Leckman and Donald J. Cohen; 13. Receptor studies in sleep and sleep disorders Mortimer Mamelak; 14. Receptor localization in neuropsychiatry James K. Wamsley and Ted M. Dawson; 15. Brain tissue transplantation:: applications to neurological research Stephen B. Dunnett and Anders Björklund; Index.
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