Leading international and authoritative experts presents state-of-the-art knowledge and key principles in the clinical diagnosis, pathology, and investigation of motor neuron disorders. The text features essential information on the diagnosis management, and prognosis of patients with amyotrophic lateral sclerosis, as well as the changes that have been brought about by advances in research and science.
Key Principles in the Clinical Diagnosis, Pathology & Investigation of Motor Neuron Disorders 1 Clinical Principles in the Differential Diagnosis of Motor Neuron Disorders 2 Pathology of Motor Neuron Disorders 3 Neurophysiological Investigation of Motor Neuron Disorders 4 Neuroimaging in Notor Neuron Disorders
Motor Neuron Disease/Amyotrophic Lateral Sclerosis 5 Clinical Aspects of ALS/MND 6 Cognitive Impairment in the Motor Neuron Disease 7 Epidemiology of ALS/MND 8 Genetic Aspects of ALS/MND 9 Cellular Bioligical Effects of SODI Mutations 10 Excitotoxicity & Oxidative Stress in the Pathogenesis of ALS/MND 11 Mitochondrial Dysfunction in Amyotrophic Lateral Sclerosis (ALS) 12 Cyto skeletal Abnormatlities in ALS/MND 13 The role of Microglia in Amyotrophic Lateral Sclerosis 14 Cell Death Pathways in Amyotrophic Lateral Sclerosis 15 Factors Underlying the Selective Vulnerability of Motor Neurons to Neurodegeneration
Other Motor Neuron Disorders 16 Spinal Muscular Atrophy 17 Kennedys Disease 18 Hereditary Spastic Paraparesis
Therapeutics of Motor Neuron Disorders 19 Quality of Life & Psychosocial Aspects of Care of Patients with ALS 20 Sympton Control in ALS/MND 21 Disease Modifying Therapies in Motor Neuron Disorders: The Present Position and Petential Future Developments FM
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