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Human Hypothalamus: Basic and Clinical Aspects, Part II

Human Hypothalamus: Basic and Clinical Aspects, Part II

Handbook of Clinical Neurology (Series Editors: Aminoff, Boller and Swaab)

9780444514905
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Description
This volume in the Handbook of Clinical Neurology (Series Editors:: Michael J. Aminoff, Department of Neurology, University of California, San Francisco, USA; François Boller, Bethesda, USA; Dick F. Swaab, Netherlands Institute for Neuroscience, Amsterdam, the Netherlands)is the first major account of the human hypothalamus. Part II is system and disease oriented and deals with the clinic, and with the neuropathology, neurobiology and genetics of vascular disorders, disorders of development and growth (including e.g. anencephaly, septo-optic dysplasia and other midline defects), hypothalamic and pineal tumors, infections, neuroimmunological disorders such as neurosarcoidosis, multiple sclerosis, and Langerhans-cell histiocytosis. After the neuropathology of the neurohypophysis has been dealt with, the background of the different forms of diabetes insipidus and other drinking disorders, such as polydipsia and adipsia, inappropriate secretion of vasopressin, and Wolfram syndrome are presented. Eating disorders such as, e.g. Prader-Willi syndrome, anorexia and bulimia nervosa, are presented as typical hypothalamic diseases. Genetic disorders causing a defect in the migration of hypothalamic neurons are the basis of Kallmann syndrome. Sexual differentiation of the brain is related to transsexuality and homo/heterosexuality.
Product Details
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9780444514905
9780444514905

Data sheet

Publication date
2003
Issue number
1
Cover
hard cover
Pages count
616
Weight (g)
2019
  • Part II. Neuropathology of the Human Hypothalamus and Adjacent Brain Structures.

    17. Vascular supply and vascular disorders. 17.1 Blood supply to the hypothalamus and pituitary. 17.2 Vascular lesions of the hypothalamus. 17.3. Choroid plexus of the third ventricle. 18. Disorders of development and growth. 18.1 Anencephaly. 18.2 Transsphenoidal encephalocele and empty sella syndrome. 18.3 Congenital midline defects: optic nerve hypoplasia and septo-optic dysplasia (De Morsiers syndrome). 18.4 Dystopia of the neurohypophysis. 18.5 The optic chiasm. 18.6 The growth hormone axis in development and aging. 18.7 Hydrocephalus. 18.8 Septum pellucidum abnormalities. 19. Tumors. 19.1 Symptoms due to hypothalamic tumors. 19.2 Germinoma and teratoma. 19.3 Hamartoma. 19.4 Glioma. 19.5 Craniopharyngioma, Rathkes cleft cysts and xanthogranuloma. 19.6 Dermoid and epidermoid tumors. 19.7 Pineal region tumors. 19.8 Tuberous sclerosis (Bourneville-Pringle syndrome) and tumors of the hypothalamus. 19.9 Metastases. 19.10 Other tumors. 20. Hypothalamic infections. 20.1 Inflammatory conditions affecting the hypothalamus. 20.2 Encephalitis lethargica (Von Economos encephalitis). 20.3 Acquired immunodeficiency syndrome (AIDS). 21. Neuroimmunological disorders. 21.1 Neurosarcoidosis of the hypothalamus. 21.2 Multiple sclerosis (MS) and the hypothalamus. 21.3 Langerhans cell histiocytosis (Hand-Schüller-Christian disease; histiocytosis-X).
    21.4 Other neuroimmunological hypothalamic disorders and lesions. 22. Drinking disorders. 22.1 Pathology of the neurohypophysis. 22.2 Diabetes insipidus. 22.3 Primary polydipsia and adipsia. 22.4 Nocturnal diuresis. 22.5 Vasopressin hypersecretion in diabetes mellitus. 22.6 Inappropriate secretion of vasopressin. 22.7 Wolframs syndrome. 23. Eating disorders. 23.1 Prader-Willi syndrome. 23.2 Anorexia nervosa and bulimia nervosa. 23.3 Other eating disorders. 24. Reproduction, olfaction and sexual behavior. 24.1 Disorders of gonadotropic hormone regulation. 24.2 Olfaction, anosmia, the vomeronasal organ (Jacobsons organ) and the embryology of LHRH neurons. 24.3 Kallmanns syndrome. 24.4 Klinefelters syndrome or testicular dysgenesis. 24.5 Sexual differentiation of the brain and sexual behavior. 25. Hypothalamic lesions following trauma and iatrogenic disorders. 25.1 Head/brain injury. 25.2 Neuroleptic malignant syndrome. 25.3 Hypothalamic injury by radiation. 25.4 Lesion of the pituitary stalk. 26. Hypothalamic involvement in psychiatric disorders. 26.1 Psychiatric symptoms due to tumors of the third ventricle. 26.2 Attacks of laughter (gelastic epilepsy). 26.3 Ventromedial hypothalamus syndrome and the effect of lesions on aggression. 26.4 Depression and mania. 26.5 The hypothalamus in mental deficiency. 26.6 Obsessive-compulsive disorder. 26.7 Anxiety disorders. 26.8 Fatigue syndromes. 26.9 Aggressive behavior. 27. Schizophrenia and autism. 27.1 Schizophrenia. 27.2 Autism. 28. Periodic disorders. 28.1 Kleine-Levin syndrome (periodic somnolence and morbid hunger). 28.2 Spontaneous periodic fever, hypothermia, Shapiro syndrome and periodic Cushings syndrome. 28.3 Acute intermittent porphyria. 28.4 Narcolepsy. 28.5 Epileptic seizures. 29. Neurodegenerative disorders. 29.1 Alzheimers disease and the hypothalamus. 29.2 Dementia with argyrophilic grains. 29.3 Parkinsons disease. 29.4 Huntingtons disease. 29.5 Wernickes encephalopathy, Korsakoffs psychosis and Marchiafava-Bignami disease. 29.6 Adrenomyeloneuropathy, adrenoleukodystrophy and hypothalamic-pituitary dysfunction. 29.7 Other neurodegenerative disorders. 30. Autonomic disorders. 30.1 Temperature regulation. 30.2 Disturbed thermoregulation. 30.3 Cardiovascular regulation. 30.4 Cardiovascular disturbances. 30.5 Circumventricular organs: lamina terminalis, subfornical organ and autonomic regulation. 30.6 Micturition. 30.7 Sleep. 31. Pain and addiction. 31.1 Opioid peptides and other addictive compounds. 31.2 Pain and the hypothalamus. 31.3 Headache. 32. Miscellaneous hypothalamic syndromes. 32.1 Idiopathic hypothalamic syndrome of childhood, a paraneoplastic syndrome. 32.2 Hypothalamic atrophy, Leighs disease and Cornelia de Langes syndrome. 32.3 Diencephalic idiopathic gliosis. 32.4 Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome. 32.5 Agenesis of the diencephalon. 32.6 Tourettes syndrome. 33. Brain death and dead neurons. References. Subject Index for Part I and Part II.
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