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Mims' Medical Microbiology and Immunology
Mims' Medical Microbiology and Immunology

Medical Microbiology

9780723432593
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Description
The latest edition of this internationally popular textbook has been substantially updated and improved to keep it at the forefront of clinical microbiology. Its systems-based approach emphasizes the microbiology of the agents responsible for the diseases that affect individual areas of the body. Over 250 full-color diagrams clarify complicated concepts-paired with color clinical photographs that demonstrate the clinical relevance of the science.
Product Details
Mosby
47903
9780723432593
9780723432593

Data sheet

Publication date
2003
Issue number
3
Cover
paperback
Pages count
648
Weight (g)
2077
  • I. THE ADVERSARIES: PARASITES
    1. Microbes as Parasites
    The Varieties of Microbes . Living Inside or Outside Cells . Systems of Classification
    The Organisms
    2. Bacteria
    3. Viruses
    4. Fungi
    5. Protozoa
    6. Helminths and Arthropods
    7. Prions
    8. The Host-Parasite Relationship
    The Normal Flora . Symbiotic Association . The Characteristics of Parasitism . The Evolution of Parasitism
    II. THE ADVERSARIES: HOST DEFENSES
    9. The Innate Defenses of the Body
    Defense Against Entry into the Body . Defenses Once the Microorganism Penetrates the Body
    10. Adaptive Responses - a Quantum Leap in Effective Defense
    The Role of Antibodies . The Role of T Lymphocytes/MHC . Extracellular Attack on Large Infectious Agents . Local Defenses at Mucosal Surfaces
    11. The Cellular Basis of Adaptive Immune Responses
    B and T Cell Receptors . Selection & Clonal Expansion of Lymphocytes . Role of Memory Cells . T-independent and T-dependent Antigens . Cytokines . Regulatory Mechanisms . Tolerance Mechanisms
    III. CONFLICTS
    12. Conflicts: Background to Infectious Disease
    Host-Parasite Relationships . Causes of Infectious Diseases . The Biologic Response Gradient
    13. Entry, Exit and Transmission
    Sites of Entry . Exit and Transmission . Types of Transmission . Transmission from Animals
    14. Innate Defenses in Action
    Complement . C-reactive Protein . Phagocytosis . Cytotoxicity by Lymphocytes and Natural Killer Cells . Cytotoxic Lipids . Cytokines . Fever
    15. Spread and Replication
    Features of Surface and Systemic Infections . Mechanisms of Spread through the Body . Genetic Determinants of Spread and Replication . Other Factors Affecting Spread and Replication
    16. Adaptive Immunity in Action
    17. Parasite Survival Strategies and Persistent Infections
    Parasite Survival Strategies . Concealment of Antigens . Antigenic Variation . Immunosuppression . Persistent Infections
    18. Pathologic Consequences of Infection
    Pathology Due to Direct Effects of the Microorganism . Pathologic Activation of Innate Immune Mechanisms . Pathologic Consequences of the Adaptive Immune Response . Skin Rashes . Viruses and Cancer . Microbes & Diseases of obscure origin
    IV. CLINICAL MANIFESTATIONS AND DIAGNOSIS OF INFECTIONS BY BODY SYSTEM
    19. Upper Respiratory Tract Infections
    The Clinical Manifestations of Infection . The Common Cold . Pharyngitis and Tonsillitis . Otitis and Sinusitis . Acute Epiglottitis . Oral Cavity Infections . Laryngitis and Tracheitis . Diphtheria . Summary
    20. Lower Respiratory Tract Infections
    Acute Infections of the Lower Respiratory Tract . Chronic Infections of the Lower Respiratory Tract . Parasitic Infections of the Lower Respiratory Tract . Summary
    21. Urinary Tract Infections
    Acquisition and Etiology . Pathogenesis of UTIs . Clinical Features and Complications . Laboratory Diagnosis of UTIs . Treatment of UTIs . Prevention of Urinary Tract Infections . Summary
    22. Sexually Transmitted Diseases
    STDs and Sexual Behavior . Syphilis . Gonorrhea . Chlamydial Infection . Other Causes of Inguinal Lymphadenopathy . Mycoplasmas and Non-gonococcal Urethritis . Other Causes of Vaginitis and Urethritis . Genital Herpes . Human Papillomavirus Infection . HIV and AIDS . Opportunistic STDs . Arthropod Infestations . Summary
    23. Gastrointestinal Tract Infections
    Diarrheal Diseases . Helicobacter pylori and Gastric Ulcer Disease . Parasites and the Gastrointestinal Tract . Systemic Infection Initiated in the Gastrointestinal Tract . Hepatitis & other diseases of liver . Summary
    24. Obstetric and Perinatal Infections
    Infections Occurring in Pregnancy . Congenital Infections . Infections Occurring Around the Time of Birth
    25. Central Nervous System Infections
    Invasion of the Central Nervous System . The Bodys Response to Invasion . Bacterial Meningitis . Fungal Meningitis . Protozoal Meningitis . Viral Meningitis . Encephalitis . Neurologic Diseases of Possible Viral Etiology . Slow Virus Infection . Brain Absceses . Encephalopathy Due to Scrapie-type Agents . Postvaccinial and Postinfectious Encephalitis . CNS Disease Due to Helminth Parasties . Tetanus and Botulism . Summary
    26. Infections of the Eye
    Conjunctivitis . Infection of the Deeper Layers of the Eye
    27. Infections of Skin
    Infections of the Skin . Bacterial Infections of Skin, Soft Tissue and Muscle . Mycobacterial Diseases of the Skin . Fungal Infections of the Skin . Parasitic Infections of the Skin . Mucocutaneous Lesions Caused by Viruses . Other Infectious Causes of Maculopapular Rashes . Summary
    28. Infections of Muscle, Joints, Bone and Hemopoietic System
    Kawasaki Syndrome . Muscle infections . Joint and Bone Infections . Infections of the Hemopoietic System
    29. Worldwide Virus Infections
    Measles . Mumps . Rubella . Cytomegalovirus Infection . EBV Infection . Other Human Herpesvirus (HHV) Infections . Smallpox . Summary
    30. Vector-borne Infections
    Arboviruses and Hemorrhagic Fevers . Rickettsial Infections . Borrelia Infections . Protozoal Infections . Helminth Infections
    31. Zoonoses
    Arenavirus Infections . Korean Hemorrhagic Fever . Marburg and Ebola Hemorrhagic Fevers . Q Fever . Anthrax . Plague . Yersinia enterocolitica Infection . Tularemia . Pasteurella multocida Infection . Leptospirosis . Rat Bite Fever . Brucellosis . Helminth Infections
    32. Fever of Unknown Origin
    Definitions of Fever of Unknown Origin . Causes of FUO . Investigation of Classical FUO . Treatment of FUO . FUO in Specific Patient Groups . Infective Endocarditis . Summary
    33. Infections in the Compromised Host
    The Compromised Host . Deficient Innate Immunity . Deficient Adaptive Immunity . Pathogens that Infect the Compromised Host . Clinical management of compromised host . Summary
    V. DIAGNOSIS AND CONTROL
    34. Strategies for Control: An Introduction
    Epidemiologic considerations . Importance of diagnosis . Chemotherapy Versus Vaccination . Control Versus Eradication
    35. Diagnosis of Infection and Assessment of Host Defense Mechanisms
    Aims of the Clinical Microbiology Laboratory . Specimen Protocols . Non-cultural Techniques for the Laboratory Diagnosis of Infection . Cultivation (Culture) of Microorganisms . Identification of Microorganisms Grown in Culture . Antibody Detection Methods for the Diagnosis of Infection . Assessment of Host Defense Systems
    36. Attacking the Enemy: Antimicrobial Agents and Chemotherapy
    Selective Toxicity Discovery and Design of Antimicrobial Agents . Classification of Antibacterial Agents . Inhibitors of Cell Wall Synthesis . Inhibitors of Protein Synthesis . Inhibitors of Nucleic Acid Synthesis . Other Agents That Affect DNA . Inhibitors of Cytoplastic Membrane Function . Antibacterial Agents in Practice . Antiviral Agents . Antifungal and Antiparasitic Agents . Use and Misuse of Antimicrobial Agents . Resistance to Antimicrobials . Summary
    37. Boosting Host Defense: Vaccination
    The Aims of Vaccination . Requirements of a Good Vaccine . Types of Vaccine . Special Considerations . Current Vaccine Practice . Community-based Control by Vaccination . Factors Influencing the Success of Vaccination
    38. Passive and Non-specific Immunotherapy
    Passive Immunization with Antibody . Non-specific Cellular Immunostimulation . Correction of Host Immunodeficiency
    39. Hospital Infection: Sterilization and Disinfection
    Common Hospital-acquired Infections . Important Causes of Hospital Infection . Sources and Routes of Spread of Hospital Infection . Host Factors and Hospital Infection . The Consequences of Hospital Infection . Prevention of Hospital Infection . Investigating Hospital Infection . Sterilization and Disinfection . Deciding Whether Sterilization or Disinfection Should Be Used . Techniques for Sterilization . Controlling Sterilization and Disinfection . Summary
    Pathogen Review
    Answers
    Index
    Appendix I: Protocols for Specimen Processing
    Protocols for Specimen Processing . Specimen Collection . Transport of Specimens . Specimen Processing

See next edition:

Mims' Medical Microbiology and Immunology
Mims' Medical Microbiology and Immunology
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