In this issue of Radiologic Clinics, guest editors Drs. Myles Taffel and Satheesh Krishna bring their considerable expertise to the topic of Genitourinary Imaging. Top experts discuss topics such as imaging of the penis and urethra, imaging of the retroperitoneum, inflammatory conditions of the GU tract; imaging of the penile prosthesis; MRI evaluation of the testes and scrotum, imaging biomarkers, photon counting applications in genitourinary imaging, and much more.