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Single-Molecule Studies of Nucleic Acids and Their Proteins

Single-Molecule Studies of Nucleic Acids and Their Proteins

9780198530923
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Description
This book provides the basis for understanding the elastic properties of nucleic acids (DNA, RNA), the methods used to manipulate them (e.g. optical, magnetic and acoustic tweezers and traps), and how to observe their interactions with proteins (e.g. fluorescence microscopy, FCS, FRET, etc.). It then exemplifies the use of these various methods in the study of three families of DNA enzymes:: polymerases, helicases and topoisomerases. The book aims not to be exhaustive, but rather tostimulate the imagination of readers in the application of these single molecule approaches to the study of DNA/RNA and their interactions.
Product Details
OUP Oxford
88170
9780198530923
9780198530923

Data sheet

Publication date
2018
Issue number
1
Cover
hard cover
Pages count
240
Dimensions (mm)
171 x 246
Weight (g)
614
  • Introduction to DNA; Manipulating DNA; Fluorescence Spectroscopy and Microscopy Techniques; The Mechanical Properties of Nucleic Acids; Structural Transitions in DNA; Single Molecule Studies of DNA-associated Motors; DNA and RNA Polymerases; DNA Helicases; Topoisomerases; Conclusions;
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