In this issue of Immunology and Allergy Clinics, guest editors Drs. Glenn T. Furuta and Dan Atkins bring their considerable expertise to the topic of Eosinophilic Gastrointestinal Diseases. Top experts provide a multilayered examination of the current state of knowledge in the field, compiling an issue that serves as a convenient reference for the evaluation and management of eosinophilic esophagitis (EoE) and eosinophilic gastrointestinal diseases (EGIDs).