Experimental surgery is an important link for the development in clinical surgery, research and teaching. Experimental surgery was part of the most important surgical discoveries in the past century. Since 1901 nine Nobel Prizes have been awarded to the pioneers had remarkable achievements in the basic or practical surgery. In recent 20 years, experimental surgery has achieved new advances, like laparoscopic and robotic surgery, tissue engineering, and gene therapy which are widely applied in clinic surgery. The present book covers wide experimental surgery in preclinical research models subdivided in two volumes. Volume I introduces surgical basic notions, techniques, and different surgical models involved in basic experimental surgery and review the biomechanical models, ischemia/reperfusion injury models, repair and regeneration models, and organ and tissue transplantation models, respectively. Volume II introduces several specific experimental models such as laparoscopic and bariatric experimental surgical models. The second volume also introduces graft-versus-host disease, and other experimental models. Review the advances and development of recent techniques such as tissue engineering, organ preservation, wound healing and scarring, gene therapy and robotic surgery. The book documents the enormous volume of knowledge we have acquired in the field of experimental surgery. In this book, we have invited experts from the United States, Canada, France, Germany, China, Japan, Korea, UK, Sweden, Netherland, Hungary and Turkey to contribute 36 chapters in the fields of their expertise. These two volumes are the compilation of basic experimental surgery and updated advances of new development in this field that will be invaluable to surgeons, residents, graduate students, surgical researchers, physicians, immunologists, veterinarians and nurses in surgery.
Preface; Laparoscopic Experimental Surgery Models; Experimental Models of Sepsis; Bariatric Experimental Surgery Models; Animal Models of Heart Failure; Hepatopancreatobiliary Surgery Experimental Models; Animal Models of Acute Graft-Versus-Host & Host-Versus-Graft Responses & Diseases; Microfluidic Devices & Micro-Dissected Tissue to Predict Therapeutic Response in Patients with Prostate Cancer; Of Mice & Rats: Animal Models for Use in Laparoscopy & Laparotomy with Human; Organ Bioengineering through Decellularization & Recellularization Approaches; Wound Healing & Scarring; Organ Preservation; Machine Organ Preservation; Microcirculation; Experimental Gene Therapy Using Naked DNA; Robotic Surgery in Experimental Medicine; Index.
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