This comprehensive textbook, spearheaded by the Sleep Research Society, presents an in-depth exploration of sleep and circadian scienceThe book commences by defining sleep and circadian rhythms and discussing various research methods employed in the field. It summarizes the current understanding of brain mechanisms, physiology, and genetics related to sleep and circadian rhythms, as well as their ontogeny and phylogeny. The text also examines the evidence supporting the restorative functions of sleep for both the brain and the body. Finally, it delves into the pathophysiology and demographics of major sleep disorders, theeffects of sleep loss on performance and safety, and relevant sleep health policies.Authored by renowned experts in the field, the content provides a succinct summary of the current understanding of sleep and circadian rhythms, making it an ideal resource for upper-level undergraduate and introductory graduate courses. Additionally, the book serves as an invaluable reference for physicians seeking certification in Sleep Medicine and caters to individuals interested in gaining a scholarly understanding of sleep and circadian science.
Section 1: Basic Definitions, Advanced Methods, History; Chapter 1: Definitions and Basic Methods for Assessing Sleep; Chapter 2: Circadian Biology: Definitions and Fundamental Methods of Investigation; Chapter 3: Advanced Methods to Study Sleep; Chapter 4: Genetic and Omic Methods to Study Sleep and Circadian Rhythms; Chapter 5: History of Sleep Research; Section 2: Brain Mechanisms; Chapter 6: Neural Circuits and Neurotransmitter Systems Regulating Sleep-Wake Cycles; Chapter 7: Sensory-motor processing during sleep; Chapter 8: Fundamentals of the Circadian Clock System: Molecular Clock and Systems-Level Features; Chapter 9: Interactions of sleep-wake history and circadian rhythms in human sleep; Chapter 10: Genetics of sleep and its regulation; Chapter 11: The neurobiology of dreaming; Section 3: Physiology in Sleep; Chapter 12: Sleep and the Autonomic Nervous System; Chapter 13: Respiratory Physiology; Chapter 14: Sleep and Thermoregulation; Chapter 15: Sleep and Endocrinology; Chapter 16: Sleep and Immune Health; Section 4: Phylogeny and Ontogeny of Sleep; Chapter 17: The Evolution of Sleep: Using simple brains to study the complexity of sleep.; Chapter 18: Evolution of Vertebrate Sleep States; Chapter 19: Fundamental Features of Sleep in Early Development; Chapter 20: Sleep in Humans from Fetus through Adolescence; Chapter 21: Sleep in Humans - Older Adults; Section 5: Effects of Wake and Associated Hypothesized Functions of Sleep; Chapter 22: Influence of Behavioural States on Brain Energetics and Maintenance; Chapter 23: Learning, Memory, and Synaptic Plasticity; Chapter 24: Mood, Motivation, and Emotion Regulation; Section 6: Sleep Disorders and Sleep in Medical Conditions; Chapter 25: Sleep-related breathing disorders; Chapter 26: Insomnia Disorder; Chapter 27: Narcolepsy and Idiopathic Hypersomnia; Chapter 28: Circadian Rhythm Disorders; Chapter 29: Parasomnias; Chapter 30: Pharmacotherapy of Sleep Disorders; Chapter 31: Cognitive/Behavioural Approaches for Treating Sleep Disorders; Chapter 32. Sleep and circadian rhythms in psychiatric and neurological disorders; Chapter 33: Sleep in Medical Disorders; Section 7: Sleep and Society; Chapter 34: Population-Level Sleep, Sleep Disorders, and Sleep Disparities; Chapter 35: Impact of Sleep Loss on Alertness, Performance, and Safety; Chapter 36: Sleep health and policy;
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