Written and edited by global opinion leaders in the area of lymphedema treatment, Lymphedema:: Complete Medical and Surgical Management, 2nd Edition, provides state-of-the-art, comprehensive guidance on this increasingly common condition. Now fully up to date, this practical resource covers anatomy, physiology, lymphangiogenesis, pathophysiology, clinical presentation, diagnosis and management strategies , including surgical, conservative and pharmacologic therapy; as well as research and future directions. Abundantly illustrated throughout and featuring numerous videos online, it’s your one-stop reference for improving outcomes for patients with various types of lymphedema.
Section 1: Current concepts in Lymphedema 1. Lymphedema: Lack of solutions to a clinical problem Patients prospective and existing evidence: 2A. Patients` prospective and real expectations on Lymphedema 2B. Myths and facts in Lymphedema 2C. How to find accurate sites on the internet 2D. Evidence mapping of Lymphedema treatment 2E. International consensus documents (Conservative + Surgical Consensus)
Section 2: Anatomy, Pathophysiology and Lymphangiogensis Embryology and Applied Anatomy 3A. Embryology of lymphatic system 3B. Anatomy of the lymphatic pathways 3C. Applied Lymphatic Anatomy 4. Hydromechanics of intercellular fluid and lymph Lymphangiogenesis: 5A. Mechanism of lymphangiogenesis and neolymphangiogenesis 5B. Impact of genetics on lymphangiogenesis 5C. Relationship between fat tissue and lymphangiogenesis 6. Immune regulation by the peripheral lymphatics 7. Pathophysiology of primary and secondary Lymphedema 8. Lymphatic malformations
Section 3: Clinical Presentation of Lymphedema Lymphedema presentation according to anatomical regions: 9A. Head and Neck Lymphedema 9B. Upper limb and Breast Lymphedema 9C. Lower limb Lymphedema 9D. Genital Lymphedema 9E. Dermatologic implications of Lymphedema 9F. Oncology and Lymphedema 10. Obesity-induced Lymphedema 11. Lymphedema in paediatric patients 12. Post trauma Lymphedema
Section 4: Diagnosis of Lymphedema 13. Medical History, physical examination and Measuring Methods 14. Biomarkers Imagining modalities: 15A. Introduction to radiology in lymphedema 15B. Non-contrast MR lymphography 15C. Indocyanine green lymphography ICG 15D. Magnetic resonance lymphangiography 15e. High-definition US 16. Lymphedema Clinical Staging 17. Differential Diagnosis of lymphedema
Section 5: Conservative treatments of Lymphedema 18. Pharmacological treatments of Lymphedema Current physiotherapy treatment options for Lymphedema: 19A. Introduction to physiotherapy in Lymphedema 19B. Exercises 19C. Lymphatic drainages 19D. Compression therapies 19E. Alternative treatments (Yoga, acupuncture, Etc) 19F. Immediate post-operative physiotherapy treatment 19G. Compliance and adherence to lymphedema treatment Lymphedema patients ‘care: 20A. Lymphedema and nursing care 20B. Nutrition and Diet for Lymphedema 20C. Psychological impacts of lymphedema
Section 6: Surgical treatment of Lymphedema Patient`s Selection for Surgery: 21A. Accurate patients’ selection 21B. Interventional timing 22. Excisional approaches for Lymphedema treatment 23. Liposuction Lymphaticovenous bypass Operations: 24A. Basic LV bypass concept 24B. Multiple distal LV bypass 24C. ELVA Concept 24D. Lymph node-venous anastomosis 24E. Tips and Tricks for LV Bypass: Making it easy 25. Lymphatic graft Vascularized lymph node transplantation: 26A. Basic VLNT Concept 26B. Recipient site selection in VLNT 26C. VLNT donor selection: Submental 26D. VLNT donor selection: Supra Clavicular 26F. VLNT donor selection: Thoraco-dorasl 26G. VLNT donor selection:Omental 26H. VLNT donor selection: Mesenteric 26I. VLNT donor selection:Groin 26J. Minimizing donor site morbidity & Reverse lymphatic mapping 26K. Vascularized functional lymphatic tissue transfer 26L. Lymph interpositional flap transfer (LIFT) 26M. Alternative Approaches for Lymphedema Treatment 27. Nursing care in Lymphedema surgery
Section 7: Prophylactic treatment of Lymphedema Prophylactic lymphedema treatments during oncological surgeries: 28A. Breast and upper limbs 28B. Lower limbs 28C. Pelvic surgeries 28D. Immediate lymphatic reconstruction ILR (LYMPHA Technique) 28E. Targeted lymphatic axillary repair (T-LAR) Lymphedema: from screening to prevention 29A. Sentinel lymph node outcomes 29B. Prophylactic treatments with immediate breast reconstruction 29C. Screening and early detection of lymphedema & Subclinical lymphedema management
Section 8: Special Topics related to Lymphedema 30. Filariasis 31. Combined lymphatic and venous failure: Phlebolymphedema Lipedema: 32A. Lipedema Physiopathology 32B. The Challenges of Lipedema Diagnosis 32C. Lipo-lymphedema vs Lipedema Central lymphatic dysfunctions 33A. Chylothorax 33B. Ascites 34. Lymphocele 35. Mixed vascular and lymphatic malformation
Section 9: Multicdisplinary approach & Expected outcomes 36. Multidisciplinary management of Lymphedema 37. Short- and long-term Follow up 38. Quality of life measurement instruments
Section 10: Research and future perspectives 39. Lymphangiogenic growth factors and receptors 40. Molecular bases of medical treatment of Lymphoedema 41. Scaffold and biological matrix to build a missing lymphatic system 42. Animal models in Lymphedema 43. Creating a Lymphedema Framework 44. Robotic Surgery 45. Artificial Intelligence
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