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Molecular Imaging

Molecular Imaging

9781607950059
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Description
The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters.

Given the multidisciplinary nature of the field, the book is broken into six different sections:: “Molecular Imaging technologies”, “Chemistry”, “Molecular Imaging in Cell and Molecular Biology”, “Applications of Molecular Imaging”, “Molecular Imaging in Drug Evaluation” with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Product Details
McGraw Hill / Europe, Middle East & Africa
46974
9781607950059
9781607950059

Data sheet

Publication date
2010
Issue number
1
Cover
hard cover
Pages count
1380
Dimensions (mm)
225 x 288
Weight (g)
4

  • Part I: Molecular Imaging Technologies

    1: Imaging of structure and function with PET/CT
    2: PET/MRI
    3: SPECT and SPECT/CT
    4: Principles of micro x-ray computed tomography
    5: Small Animal SPECT, SPECT/CT, and SPECT/MRI
    6: Instrumentation and methods to combine small animal PET with other imaging modalities
    7: Functional Imaging using Bioluminescent Imaging
    8: Optical Multimodality
    9: Fiber Optic Fluorescence Imaging
    10: Fluorescence Tomography
    11: Endomicroscopy
    12: Intravital Microscopy
    13: Diffuse Optical Tomography
    14: Ultrasound
    15: Molecular Photoacoustic Tomography
    16: Optical Projection Tomography
    17: Signal Post Processing/Image Reconstruction

    Part II: Chemistry of Molecular Imaging

    18: Chemistry of Molecular Imaging: an overview
    19: Radiochemistry of PET
    20: Radiochemistry of SPECT
    21: Nanochemistry for Molecular Imaging
    22: Newer Bioconjugation Methods
    23: Targeted Antibodies and Peptides
    24: Hyperpolarized 13C magnetic resonance imaging – Principles and applications
    25: MR Imaging Agents
    26: Optical Imaging Agents
    27: Ultrasound Contrast Agents
    28: Multimodality Agents
    29: “Click Chemistry”: Applications to Molecular Imaging
    30: The “One-Bead-One-Compound” Combinatorial Approach toIdentifying Molecular Imaging Probes
    31: Chemical Biology Approaches to Molecular Imaging
    32: Theranostics: Agents for diagnosis and therapy
    33: Magnetic Nanoparticles
    34: Fluorocarbon Agents For Quantitative Multimodal Molecular Imaging and Targeted Therapeutics
    35: Aptamers for Molecular Imaging
    36: Toxicology

    Part III: Molecular Imaging in Cell & Molecular Biology

    37: Overview of Molecular and Cell Biology
    38: Systems Biology
    39: Protein Engineering
    40: Phage Display for Agent Development
    41: Molecular Imaging of Gene Therapy
    42: Developing diagnostic and therapeutic viral vectors
    43: Cell Voyeurism using Magnetic Resonance Imaging
    44: Tumor vasculature
    45: Hypoxia Imaging
    46: Protein-Protein Interaction
    47: Fluorescence Reporters/Activatable Cell Penetrating Peptides
    48: Imaging of Signaling Pathways

    Part IV: Applications of Molecular Imaging

    49: Molecular and Functional Imaging of the Tumor Microenvironment
    50: Novel MR and PET Imaging in the RT Planning and Assessment of Response of Malignant Gliomas
    51: PET Diagnosis and Response Monitoring in Oncology
    52: MRS Treatment Response and Detection
    53: MRI Treatment Response Assessment – Diffusion
    54: Myocardial Metabolism
    55: Congestive Heart Failure
    56: Molecular Imaging of Atherosclerosis
    57: Thrombosis and Embolism
    58: Molecular Imaging of Stem Cells in Myocardial Infarction
    59: Central Nervous System Molecular Imaging
    60: Neuroreceptor Imaging
    61: Neurodegeneration
    62: Molecular Imaging of Autoimmune Diseases
    63: Rheumatoid Arthritis
    64: Autoimmune Diabetes
    65: Imaging in Asthma

    Part V: Molecular Imaging in Drug Evaluation

    66: Molecular and Functional Imaging in Drug Development
    67: PET Imaging Clinical Trials
    68: MR Imaging in Clinical Trials
    69: Imaging of Gene Therapy: Basis and Clinical Trials

    Part VI: Other

    70: Visualization
    71: Quantification of Radiotracer Uptake into Tissue
    72: Mining High Throughput Data for Candidate Biomarkers as Imaging and Therapeutic Targets
    73: Pharmacokinetic Modeling
    74: Cost-Effectiveness Analysis/Economics of Probe Development
    75: Regulatory and Reimbursement Process for Imaging Agents and Devices

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