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Principles of Exercise Testing and Interpretation

Including Pathophysiology and Clinical Applications

9780781748766
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Description

Thoroughly updated in its Fourth Edition, this exceptional resource is the most comprehensive, current text on the physiology and pathophysiology of exercise testing available. It is the only reference to address those disorders that can be diagnosed only through cardiopulmonary exercise testing.

Readers will find...

  • Comprehensive presentation addressing cardiovascular, metabolic, and respiratory responses to exercise—in both health and disease states.
  • Principles and rationale behind exercise testing, commonly used testing protocols, guidelines for normal and abnormal values, and tips for accurate interpretation of test results.
  • Normal test values for a range of patient groups—including children, over- and underweight patients, and the elderly.
  • More than 80 case histories, each accompanied by exercise physiology results, highlight differential diagnosis by applying basic physiological concepts to real-world examples.
  • Coverage of disorders that can be diagnosed only through cardiopulmonary exercise testing.

NEW to the Fourth Edition...

  • New chapter covering regulation of arterial and mixed venous blood gases
  • New nine-panel graphic array illustrating critical aspects of exercise testing
  • Updated flow charts to help with clinical interpretation and differential diagnosis
Product Details
42615
9780781748766
9780781748766

Data sheet

Publication date
2004
Issue number
4
Cover
hard cover
Pages count
568
Dimensions (mm)
216 x 279
Weight (g)
1633
    1. Exercise Testing and Interpretation: An Overview

      • Why Measure Gas Exchange to Evaluate Cardiovascular Function and Cellular Respiration?
      • Cardiac Stress Test and Pulmonary Stress Test: Nomenclature and Fallacies
      • Cell Respiration and Bioenergetics
      • Normal Coupling of External to Cellular Respiration
      • Quantifying State and Time Course of Cellular Respiration from Measurements Of External Respiration
      • Patterns of Change in External Respiration (O2 Uptake and CO2 Output) as Related to Function, Fitness and Disease
      • Factors Limiting Exercise
        • Fatigue
        • Dyspnea
        • Pain
      • Evidence of Systemic Dysfunction Uniquely Revealed by Integrative Cardiopulmonary Exercise Testing
    2. Physiology of Exercise

      • Skeletal Muscle
        • Mechanical Properties and Fiber Types
        • Energetics
      • Oxygen Cost of Work
        • Work Efficiency
        • VO2 Non-Steady State
      • Lactate Increase
        • Lactate Increase as Related to Work Rate
        • Lactate Increase as Related to Time
        • Lactate Increase in Response to Increasing Work Rate
        • Mechanisms of Lactate Increase
      • Buffering the Exercise-induced Lactic Acidosis
      • The Anaerobic Threshold (AT) Concept
        • Identifying AT by Gas Exchange
        • Altered Physiological Responses to Exercise Above the AT
        • Anaerobic, Lactate and Lactic Acidosis Thresholds
      • Metabolic-Cardiovascular-Ventilatory Coupling
        • Cellular Respiration and High Energy Phosphate Regeneration
        • Cardiovascular Coupling to Metabolism: Muscle O2 Supply
        • Ventilatory Coupling to Metabolism
        • Effect of Dietary Substrate
      • Control of Breathing
        • Overview
        • Acid-Base Regulation
        • Physical Factors
        • Reflexes Regulating Breathing During Exercise
      • Gas Exchange Kinetics
        • Oxygen Uptake Kinetics
        • CO2 Output Kinetics
    3. Measurements During Integrative Cardiopulmonary Exercise Testing

      • What is an Integrative Cardiopulmonary Exercise Test?
      • When Should Integrative Cardiopulmonary Exercise Testing Be Used?
      • Measurements
        • Electrocardiogram
        • Maximal Oxygen Uptake (VO2max) Maximum
        • Oxygen Uptake (Peak VO2)
        • Oxygen Uptake and Work Rate
        • Pattern of Work Rate Increase and the VO2 Response
        • Upward Displacement of VO2 as A Function of Work Rate
        • Cardiac Output and Stroke Volume
        • Anaerobic (Lactate, Lactic Acidosis) Threshold (AT, LT, LAT)
        • Heart Rate-Oxygen Uptake Relationship and Heart Rate Reserve
        • Oxygen Pulse (VO2/HR) and Stroke Volume
        • Arterial Blood Pressure
        • Breathing Reserve
        • Expiratory Flow Pattern
        • Tests of Uneven VA/Q
        • Arterial Bicarbonate and Acid-Base Response
        • Tidal Volume/Inspiratory Capacity Ratio (VT/IC)
        • Measurements Unique to Constant Work Rate Exercise Testing
      • Data Display and Interpretation
    4. Pathophysiology of Disorders Limiting Exercise

      • Obesity
      • Peripheral Arterial Diseases
      • Heart Disease
        • Coronary Artery Disease
        • Myopathic Heart Disease
        • Valvular Heart Disease
        • Congenital Heart Disease
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