Completely revised, the 4th Edition of this authoritative reference delivers a wealth of new information that enables readers to identify, treat, and manage a full range of respiratory disorders more easily than ever. Edited and written by leaders in the field, the book covers the scientific principles of respiratory medicine; its foundations in basic anatomy, physiology, pharmacology, pathology, and immunology; and its clinical applications. It features a wealth of new chapters; coverage of new modalities in biotechnologic, genomic, and informational sciences; a new 2-colour design that makes it easier and quicker to access key information and complete references for further study.
PART I SCIENTIFIC PRINCIPLES OF RESPIRATORY MEDICINE
Section A Anatomy and Development of the Respiratory Tract
1. Anatomy of the Lungs 2. Lung Growth and Development 3. Genetic Approach to Lung Disease
Section B Respiratory Physiology
4. Ventilation, Blood Flow, and Gas Exchange 5. Respiratory System Mechanics and Energetics 6. Pulmonary Circulation and Regulation of Fluid Balance 7. Acid-Base Balance
11. Pulmonary Surfactant 12*. Alveolar and Distal Airway Epithelial Fluid Transport 13*. Mucus Production, Secretion, and Clearance 14. Monocytes, Macrophages, and Dendritic Cells of the Lung 15. Immune recognition and Responses
Section E Respiratory Pathology and Inflammation
16. General features of Respiratory Pathology 17. Inflammation, Injury, and Repair
PART II DIAGNOSIS AND EVALUATION OF RESPIRATORY DISEASE
Section F Diagnosis
18. History and Physical Examination 19. Microbiologic Diagnosis of Lower Respiratory Tract Infection 20. Radiographic Techniques 21. Nuclear Medicine Techniques 22. Bronchoscopy 23*. Pleuroscopy, Thoracoscopy, and Other Invasive Procedures
Section G Evaluation
24. Pulmonary Function Testing 25*. Clinical Exercise Testing 26. Preoperative Evaluation 27. Evaluation of Respiratory Impairment/Disability
PART III CLINICAL RESPIRATORY MEDICINE
Section H Symptoms of Respiratory Disease and their Management
28. Dyspnea 29. Cough 30. Chest pain
Section I Infectious Diseases of the Lungs
31. Viral Infections 32. Pyogenic Bacterial Pneumonia, lung Abscess and Empyema 33. Tuberculosis and Other Mycobacterial Diseases 34. Fungal Infections 35. Parasitic Diseases
Section J Obstructive Diseases
36. Chronic Bronchitis and Emphysema 37. Asthma 38. Cystic Fibrosis 39. Bronchiectasis 40. Disorders of the Upper Airways 41. Disorders of the Intrathoracic Airways
Section K Neoplasms of the Lung
42. Biology of Lung Cancer 43. Epidemiology of Lung Cancer 44. Bronchogenic Carcinoma 45. Lymphoma, Lymphoproliferative Diseases, and Other Primary Malignant Tumors 46. Metastatic malignant tumors 47. Benign Tumors
Section L Disorders of the Pulmonary Circulation
48. Pulmonary Thromboembolism 49. Pulmonary Vasculitis and Primary Pulmonary Hypertension 50. Pulmonary Arteriovenous Malformations and Other Pulmonary-Vascular Abnormalities 51. Pulmonary edema and Acute Lung Injury 52. Cor pulmonale
Section M Infiltrative and Interstitial Lung Diseases
53. Approach to Diagnosis and Management of the Idiopathic Interstitial Pneumonias 54. The Lungs and Connective Tissue Diseases 55. Sarcoidosis 56. Diffuse Alveolar Hemorrhage and Other Rare Infiltrative Disorders 57. Eosinophilic Lung Diseases 58. Lymphangioleiomyomatosis 59. Pulmonary Alveolar Proteinosis
Section N Environmental and Occupational Disorders
60. Occupational Asthma 61. Pneumoconioses 62. Hypersensitivity Pneumonitis 63. Air pollution 64. Acute Pulmonary Responses to Toxic Exposures 65. High Altitude 66. Diving Medicine 67. Drug-Induced Pulmonary Disease
Section O Disorders of the Pleura
68. Pleural Effusion 69. Pneumothorax, Chylothorax, Hemothorax, and Fibrothorax 70. Tumors of the Pleura
Section P Disorders of the Mediastinum
71. Tumors and Cysts of the Mediastinum 72. Pneumomediastinum and Mediastinitis
Section Q Disorders in the Control of Breathing
73. Hypoventilation and Hyperventilation Syndromes 74. Sleep Disorders
Section R Respiratory Manifestations of Extrapulmonary Disorders
75. Pulmonary Complications of Human Immunodeficiency Virus Infection 76. Pulmonary Complications of Organ Transplantation and Primary Immunodeficiencies 77. Pulmonary Complications of Heart Disease 78. Pulmonary Complications of Abdominal Disease 79. Pulmonary Complications of Hematologic Disease 80. Pulmonary Complications of Endocrine Disease 81. Pulmonary Complications of Obstetric and Gynecologic Disease 82. The lungs and Neuromuscular Disease 83. The lungs and Chest Wall Disease
Section S Management of Respiratory Failure
84. Principles of Mechanical Ventilation 85. Hypoxemic Respiratory Failure, Including ARDS 86. Acute Ventilatory Failure 87. Care at the End of Life for Patients with Respiratory Failure 88. Pulmonary Rehabilitation 89. Lung Transplantation
Section T Prevention and Control
90*. Smoking Hazards and Cessation 91*. Patient Education and Compliance