This comprehensive review of a complex area is as much about women as it is about schizophrenia, encompassing the biological, endocrinological, epidemiological, reproductive, psychological and social aspects of schizophrenia as experienced by women. Femaleness impacts significantly on the onset and nature of schizophrenia suffered by women:: the female brain develops more rapidly than the male; estrogens produce antipsychotic effects; the female brain ages differently from the male, with a massive preponderance of female very-late-onset schizophrenia which may be related to a relative excess of dopamine D2 receptors. An international, multidisciplinary team of clinicians and mental health researchers review past and current literature, assess the sex-specific issues and evaluate their therapeutic, clinical and social implications for more appropriate and effective treatments of schizophrenia in women now and in the future. It is essential reading for all clinicians, practitioners and researchers involved with mental health and also with womens health.
List of contributors; Foreword Robin MacGregor Murray; Preface David J. Castle; 1. Introduction and overview John McGrath, David J. Castle and Jayashri Kulkarni; 2. Sex differences in brain development, organization and degeneration:: are they relevant to sex differences in schizophrenia? David J. Castle; 3. Women and schizophrenia:: an epidemiological perspective David J. Castle; 4. Women and schizophrenia:: clinical aspects Mary V. Seeman and Paul Fitzgerald; 5. Hormones and psychosis Jayashri Kulkarni and George Fink; 6. Reproductive, preconceptual and antenatal needs of women with schizophrenia Joanne Barkla and John McGrath; 7. Motherhood and schizophrenia Jenny Hearle and John McGrath; 8. Women and schizophrenia:: treatment implications Paul Fitzgerald and Mary V. Seeman; 9. Overview of sex differences in schizophrenia:: where have we been and where do we go from here? Jill M. Goldstein and Richard R. J. Lewine; Index.
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