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The Benzodiazepines Crisis

The Benzodiazepines Crisis

9780197517277
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Description
Developed decades ago to treat a legitimate medical need, benzodiazepines promisingly displaced less-effective and less-safe drugs, though prescribing has since exceeded their intended use and outpaced the available data. The current situation is characterized by excessive prescribing and extended utilization beyond good therapeutic practice. Evidence indicates that prolonged use of benzodiazepines causes a wide range of adverse reactions, and withdrawal can be particularlychallenging. Misused, abused, diverted, and counterfeited, benzodiazepines have serious potential for substance use disorder, and are among the leading causes of drug-related overdose deaths. The Benzodiazepines Crisis sounds the alarm against the overuse of benzodiazepines, presenting an updated,evidence-based overview of this class of drugs and their negative consequences. Bringing together years of research, clinical expertise, and scientific evidence, this book aims to address a perceived lag between evidence and action in order to call for rational and dramatically reduced usage of benzodiazepines.
Product Details
OUP USA
93365
9780197517277
9780197517277

Data sheet

Publication date
2021
Issue number
1
Cover
paperback
Pages count
288
Dimensions (mm)
156 x 235
Weight (g)
431
  • Forewords; Reid Finlayson, Lynn Webster, Bernie Silvernail, and Carrie Silvernail; Preface; John F. Peppin, Joseph V. Pergolizzi, Jr., Robert B. Raffa, and Steven Wright; 1. Introduction: Anxiety, Insomnia, and Benzodiazepines; Michael M. Miller John Peppin; 2. The Evolution of Benzodiazepines and the Z Drugs; Jamie L. Hansen and Timothy J. Atkinson; 3. Uses, Efficacy, and Adverse Effects of Benzodiazepines; Brian Merrill and Jeffrey Guina; 4. Problems with Benzodiazepine Use in the Elderly; Jan Kitzen; 5. Benzodiazepine Receptors in the Brain; Michael H. Ossipov; 6. Benzodiazepine Receptors in the Periphery; Robert B. Raffa; 7. Benzodiazepine Withdrawal: Neurobiologic Aspects; George F. Koob; 8. Benzodiazepine Withdrawal: Clinical Aspects; Steven Wright; 9. Benzodiazepines and Pain; John F. Peppin and Steven Wright; 10. Benzodiazepines Abuse; John J. Coleman; 11. History of the Regulatory Control of Benzodiazepines; John J. Coleman; 12. Guidelines and Guidances; Jo Ann LeQuang; 13. The Benzodiazepine Legacy Patient; Jeffrey Guina and Brian Merrill; 14. Perspective; John Peppin;
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