Over the past fifty years, the case-control method, and to a lesser extent its case-based variants, have become the most important tools for the investigator of health problems. The case control method is the study of persons with the disease and a suitable control group of persons who do not have the disease. The book helps readers address a number of general and specific questions dealing with the case-control and other case-based methods, including questions of how to design andimplement a case-control study that minimizes biases, how to analyze the data to appropriately deal with confounding variables and help identify reactions, and how to interpret data and present the results from a case-control study.
From Case Investigation to the Case-Control Method; Problem Investigation and Inferences Using the Case-Control Method; Avoiding Bias in Case and Control Selection; Avoiding Information Bias in Exposure Assessment; Alternative Case-Based Designs; Analysis of Case-Control Data; Applications: Outbreak Investigation; Genetic Epidemiology for Case-Based Designs; Applications: Evaluation; Applications: Evaluation of Screening Programs; Other Applications;
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