A lucid and comprehensive review of developments made in the understanding of cellular activation phenomena in striated muscle. Basic physical, mathematical, and physiological principles are covered to a more coherent level than currently available in published literature. The book consistently draws correlations both with cellular and molecular biological information and their physiological consequences and significance. Accessible both as a survey of basic concepts and as anauthorative review of recent work in the field.The book succeeds in explaining complex biophysics in such a way that the non-expert reader obtains insights into the molecular mechanisms of muscle activation and their control mechanisms as well as providing the expert with the detailed mathematical and experimental evidence.
Previous volumes in this series; Introduction:: the activation of striated muscle; Dielectric properties and membrane function; The measurement of membrane capacitance in striated muscle; The charge-movement phenomenon in striated muscle; Functional components of the non-linear charge; Charge-movement components in skeletal muscle; Activation schemes for intramembrane charge in skeletal muscle; Quantitative description of the steady-state charge; Kinetic descriptions of the intramembrane charge; Physiological consequences of voltage-sensing processes; Implications of charge-movement components for excitation contraction coupling; References; Index;
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