Antimicrobial Chemotherapy

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Brand: OUP Oxford

ISBN: 9780199689774

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Description

Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk ofcross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents.The fully revised and updated seventh edition of Antimicrobial Chemotherapy is an essential guide to the principles of antimicrobial chemotherapy, the problem of resistance and its control through policies, antimicrobial stewardship and surveillance. The book provides an aid to informed, rational prescribing for common bacterial, fungal, parasitic and viral infections. Divided in five parts, the book cover issues specific to both the developed and developing world. Part 1 General property of antimicrobial agents discusses mechanisms of action and resistance to antibacterial, antifungal antiprotozoal, antiviral, and antiviral agents. Part 2 Resistance to antimicrobial agents provides guidance about the problem of resistance, mechanisms of acquired resistance and genetics of resistance. Part 3 General principles of usage of antimicrobial agents analysesthe use of the laboratory, general principles of the treatment of infection, dosing in special groups (extremes of age, pregnancy, obesity), safe prescribing, prophylaxis and the role of policies in antimicrobial stewardship. Part 4 Therapeutic use of antimicrobial agents provides advice about thetreatment of common infections which are described by anatomical. There are also chapters on the management of mycobacterial disease, viral infections, HIV/AIDS and parasitic infections. The final part of the book analyses the development and marketing of antimicrobial drugs.This seventh edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs.

Product Details

Brand OUP Oxford

Reference 87785

EAN13 9780199689774

ISBN 9780199689774

Data sheet

Publication date: 2015
Issue number: 7
Cover: paperback
Pages count: 432
Dimensions (mm): 171 x 246
Weight (g): 756

Part 1:: General properties of antimicrobial agents; Mechanisms of action and resistance to modern antibacterial with a history of their development; Inhibitors of bacterial cell wall synthesis; Inhibitors of bacterial protein synthesis; Synthetic antibacterial agents and miscellaneous antibiotics; Antiviral agents; Antiretroviral agents; Drugs used in the treatment of viral hepatitis; Antifungal agents; Antiprotozoal and anthelminthic agents; Part 2:: Resistance to antimicrobial agents; The problem of resistance; The genetics and mechanisms of acquired resistance; Part 3:: General principles of usage of antimicrobial agents; Laboratory investigations and the treatment of infection; General principles of the treatment of infection; Pharmacokinetic and pharmacodynamics principles; Prescribing in special groups:: effects of age, pregnancy, body weight, hepatic and renal impairment; Outpatient parenteral antimicrobial therapy; Adverse drug reactions and patient safety; Chemoprophylaxis and immunisation; Guidelines, formularies, and antimicrobial policies; Antimicrobial stewardship, surveillance of antimicrobial consumption and its consequences; Part 4:: Therapeutic use of antimicrobial agents; Respiratory tract infections; Topical use of antimicrobial agents; Urinary tract infections; Sexually transmitted infections; Gastrointestinal infections; Serious bacterial bloodstream infections; Bone and joint infections; Infections of the central nervous system; Skin and soft tissue infections; Tuberculosis and other mycobacterial diseases; Infections in immunocompromised patients including HIV/AIDs; Viral infections; Management of HIV infection; Treatment of chronic viral hepatitis; Parasitic disease; The development and marketing of antimicrobial drugs; Appendix 1:: Further Reading;