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The Sixth Edition of this well-known text has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. Emphasis is on patient-focused pharmaceutical care and on the pharmacist as a therapeutic consultant, rather than a chemist.
A new disease state management section explains appropriate therapeutic options for asthma, chronic obstructive pulmonary disease, and mens and womens health problems. Also new to this edition:: Clinical Significance boxes, Drug Lists at the beginning of appropriate chapters, and an eight-page color insert with detailed illustrations of drug structures.
Case studies from previous editions and answers to this editions case studies are available online at thePoint.
Data sheet
Historical Perspective of Medicinal Chemistry
Part I:: Principles of Drug Discovery
Part II:: Drug Receptors Affecting Neurotransmission and Enzymes as Catalytic Receptors
Part III:: Pharmacodynamic Agents
Section 1:: Drugs Affecting Central Nervous System
Chapter 18. General Anesthetics Chapter 19. Sedative-Hypnotics Chapter 20. Antiseizure Agents Chapter 21. Antidepressants Chapter 22. Psychotherapeutic Drugs:: Antipsychotic and Anxiolytic Agents Chapter 23. Hallucinogens, Stimulants and Related Drugs of Abuse Chapter 24. Opioid Analgesics Chapter 25. Drugs Used to Treat Neuromuscular Disorders:: Antiparkinsonian and Spasmolytic AgentsSection 2:: Drugs Affecting the Cardiovascular System
Chapter 26. Cardiac Agents:: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs Chapter 27. Diuretics Chapter 28. Angiotensin Converting Enzyme Inhibitors, Antagonists and Calcium Blockers Chapter 29. Central and Peripheral Sympatholytics and Vasodilators Chapter 30. Antihyperlipoproteinemics and Inhibitors of Cholesterol Biosynthesis Chapter 31. Antithrombotics, Thrombolytics, Coagulants, and Plasma ExtendersSection 3:: Drugs Affecting the Hormonal Systems
Chapter 32. Insulin and Drugs Used for the Treatment of Diabetes Chapter 33. Adrenocorticoids Chapter 34. Thyroid Function and Thyroid Drugs Chapter 35. Calcium Homeostasis Section 4:: Drugs Affecting the Immune Systems Chapter 36. Nonsteroidal Anti-Inflammatory Drugs Chapter 37. Antihistamines and Related Antiallergic and Antiulcer AgentsSection 5:: Chemotherapeutic Agents
Chapter 38. Antibiotics and Antimicrobial Agents Chapter 39. Antiparasitic Agents Chapter 40. Antifungal Agents Chapter 41. Antimycobacterial Agents Chapter 42. Cancer and Chemotherapy Chapter 43. Antiviral Agents and Protease InhibitorsPart IV:: Disease State Management
Chapter 44. Asthma and Chronic Obstructive Pulmonary Disease Chapter 45. Men Health Chapter 46. Womens HealthAppendix A:: pKa Values for Some Drugs and Miscellaneous Organic Acids and Bases
Appendix B:: pH Values for Tissue Fluids