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Aulton's Pharmaceutics

Aulton's Pharmaceutics

The Design and Manufacture of Medicines

9780702081545
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Description

The essential pharmaceutics textbook

One of the worlds best-known texts on pharmaceutics, Aultons Pharmaceutics offers a complete course in one book for students in all years of undergraduate pharmacy and pharmaceutical sciences degrees.

Thoroughly revised, updated and extended by experts in their fields and edited by Professors Kevin Taylor and Michael Aulton, this new edition includes the science of formulation, pharmaceutical manufacturing and drug delivery.

All aspects of pharmaceutics are covered in a clear and readily accessible way and extensively illustrated throughout, providing an essential companion to the entire pharmaceutics curriculum from day one until the end of the course.

  • Fully updated throughout, with the addition of new chapters, to reflect advances in formulation and drug delivery science, pharmaceutical manufacturing and medicines regulation

Designed and written for newcomers to the design and manufacture of dosage forms

Relevant pharmaceutical science covered throughout

Includes the science of formulation and drug delivery

Reflects current practices and future applications of formulation and drug delivery science to small drug molecules, biotechnology products and nanomedicines

Key points boxes throughout

Over 400 online multiple choice questions
Product Details
Elsevier
89051
9780702081545
9780702081545

Data sheet

Publication date
2021
Issue number
6
Cover
paperback
Pages count
968
Dimensions (mm)
191 x 235
Weight (g)
1980
  • Preface ....................................................................... vii
    Contributors ............................................................. ix
    Acknowledgements .................................................. xiii
    What is pharmaceutics?......................................... xv
    Kevin M.G. Taylor and Michael E. Aulton
    1. Design of dosage forms.................................. 1
    Peter York
    2. Dissolution and solubility ............................. 13
    Michael E. Aulton
    3. Properties of solutions ................................... 30
    Michael E. Aulton
    4. Surfaces and interfaces ................................... 39
    Graham Buckton
    5. Disperse systems.............................................. 50
    David Attwood
    6. Rheology........................................................... 81
    Christopher Marriott
    7. Kinetics ............................................................. 101
    Gareth R. Williams and John P. Malkinson
    8. Solid-state properties .................................... 114
    Graham Buckton
    9. Particle size analysis ..................................... 126
    Kevin M.G. Taylor
    10. Particle size reduction and size
    separation....................................................... 143
    Michael E. Aulton
    11. Mixing............................................................. 156
    Andrew M. Twitchell
    12. Powder flow................................................... 172
    Michael E. Aulton
    13. Fundamentals of microbiology................... 184
    Lara-Marie Barnes and Geoffrey W. Hanlon
    14. Pharmaceutical applications of
    microbiological techniques.......................... 208
    Lara-Marie Barnes and Norman A. Hodges
    15. Action of physical and chemical agents
    on microorganisms....................................... 229
    Lara-Marie Barnes, Geoffrey W. Hanlon and
    Norman A. Hodges
    16. Principles of sterilization ............................. 247
    Susannah E. Walsh, Katie Laird and Jean-Yves
    Maillard
    17. Sterilization in practice ................................ 257
    Jean-Yves Maillard, Katie Laird and Susannah E.
    Walsh
    18. Introduction to biopharmaceutics.............. 275
    Marianne Ashford and Kevin M.G. Taylor
    19. Gastrointestinal tract e physiology and
    drug absorption............................................. 279
    Marianne Ashford and Kevin M.G. Taylor
    20. Bioavailability e physicochemical,
    dosage form and formulation factors ........ 297
    Marianne Ashford, Kevin M.G. Taylor and
    Hala M. Fadda
    21. Assessment of biopharmaceutical
    properties ....................................................... 320
    Marianne Ashford and Kevin M.G. Taylor
    22. Dosage regimens ........................................... 343
    Soraya Dhillon and Nkiruka Umaru
    23. Pharmaceutical preformulation .................. 360
    Simon Gaisford
    24. Solutions ........................................................ 386
    Sudaxshina Murdan
    25. Clarification ................................................... 397
    Andrew M. Twitchell
    26. Suspensions ................................................... 407
    Susan A. Barker
    27. Emulsions and creams ................................. 424
    Gillian M. Eccleston
    28. Ointments, pastes, gels, cutaneous
    patches and topical sprays........................... 453
    Majella E. Lane
    29. Powders, granules and granulation ............ 463
    Michael E. Aulton
    30. Drying............................................................. 483
    Michael E. Aulton and Satyanarayana Somavarapu
    31. Tablets and compaction............................... 501
    Göran Alderborn and Göran Frenning
    32. Modified-release oral drug delivery ............ 542
    Emma L. McConnell, Christine M. Madla and
    Abdul W. Basit
    33. Coating of tablets and multiparticulates ... 558
    Stuart C. Porter
    34. Continuous manufacturing of tablets ........ 574
    Aktham Aburub and Hala M. Fadda
    35. Hard capsules ................................................ 586
    Brian E. Jones
    36. Soft capsules .................................................. 599
    Stephen Tindal
    37. Dissolution testing of solid dosage
    forms............................................................... 612
    Ana Cristina Freire, Francesca K.H. Gavins and
    Abdul W. Basit
    38. Parenteral drug delivery ............................... 626
    Robert Lowe
    39. Pulmonary drug delivery ............................. 641
    Kevin M.G. Taylor
    40. Nasal drug delivery....................................... 658
    Gary P. Martin and Alison B. Lansley
    41. Ocular drug delivery..................................... 677
    Hala Fadda, Ashkan Khalili, Peng Tee Khaw and
    Steve Brocchini
    42. Otic drug delivery ......................................... 701
    Xu Liu, Hugh Smyth and Feng Zhang
    43. Topical and transdermal drug delivery ...... 713
    Adrian C. Williams
    44. Rectal and vaginal drug delivery................. 735
    Kalliopi Dodou
    45. Preparation and delivery of
    biopharmaceuticals....................................... 752
    Ijeoma F. Uchegbu and Andreas G. Schätzlein
    46. Pharmaceutical nanotechnology and
    nanomedicines .............................................. 768
    Yvonne Perrie
    47. Radiopharmaceuticals................................... 789
    Neil Hartman and Margaret Cooper
    48. The formulation and manufacture of
    plant medicines............................................. 805
    G. Brian Lockwood
    49. Design and administration of medicines
    for paediatric and geriatric patients............ 818
    Catherine Tuleu, Mine Orlu and David Wright
    50. Packaging ....................................................... 833
    Sudaxshina Murdan
    51. Chemical stability in dosage forms............ 848
    Andrew R. Barnes and Mark Santillo
    52. Microbial contamination, spoilage and
    preservation of medicines............................ 860
    Norman A. Hodges and Lara-Marie Barnes
    53. Product stability and stability testing......... 871
    Paul Marshall
    54. Pharmaceutical quality: the application
    of pharmaceutics in medicines
    regulation ....................................................... 894
    Kevin M.G. Taylor, Majella E. Lane and
    Khalid A. Sheikh
    Self-assessment questions
    Sudaxshina Murdan
    Please check your digital version at https://studentconsult.
    inkling.com/ for self-assessment questions. See inside
    cover for registration details.
    Index.......................................................................... 915
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