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Valproic Acid: Pharmacology, Mechanisms of Action & Clinical Implications
9781624179525
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Description
Valproic acid (VPA) is a short chain fatty acid which has been used medicinally to treat conditions as far reaching as epilepsy, Bipolar disorder, migraines, and cancer. In this book, the authors research the pharmacology, mechanisms of action and clinical implications of valproic acid. Topics discussed include novel applications of the anticonvulsant drug valproic acid in cancer therapeutics; VPA treatment for epilepsy; use of fish models in fetal valproate syndrome studies; prenatal valproic acid exposure correlating with the occurrence of autism; and using 3D spheroids to determine the acute and chronic lethal thresholds of valproic acid.
Product Details
74153
9781624179525
9781624179525
Data sheet
- Publication date
- 2013
- Issue number
- 1
- Cover
- hard cover
- Pages count
- 149
- Dimensions (mm)
- 155.00 x 230.00
- Weight (g)
- 376
- Preface; Novel Applications of the Anticonvulsant Drug Valproic Acid in Cancer Therapeutics; Valproic Acid & Epilepsy:: From Basic Research to Clinical Findings; Use of Fish Models in Fetal Valproate Syndrome Study; Valproic Acid, Genetics, & Autism:: How Epimutation Alters Disease Susceptibility; Determination of Acute Lethal & Chronic Lethal Dose Thresholds of Valproic Acid using 3D Spheroids Constructed from the Immortal Human Hepatocyte Cell Line HepG2-C3A; Index.
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