Rituximab (MabThera®, Rituxan®) is a chimaeric murine/human antibody targeted against the surface antigen CD20 that is expressed on normal and malignant human mature B cells, but not stem cells or plasma cells. It is potentially the proverbial magic bullet for diseases associated with B cell disorders as well as a probe for elucidating the role of B cells in health and disease. This book explores the full spectrum of activity of Rituximab in man.
Preface; Introduction; Introduction to Rituximab:: The magic B cell Bullet; RITUXIMAB:: Pharmacology, Clinical Indications & Health Benefits; Rituximab:: update on pharmacology & clinical applications; Rituximab in the treatment of Hematological Malignancies; The Use of Rituximab in Rheumatoid Arthritis; Rituximab induced Late-onset Neutropenia.
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