An antidepressant is a psychiatric medication used to alleviate mood disorders, such as major depression and dysthymia. These medications are among those most commonly prescribed by psychiatrists and other physicians, and their effectiveness and adverse effects are the subject of many studies and competing claims. This book presents topical data on antidepressants including neuroplasticity hypothesis and depression; monitoring antidepressant therapy using heart rate variability; the role of antidepressant pharmacotherapy in the prevention of suicide; a new approach to treatment strategy of depressive disorders based on modulation of PEP activity with synthetic inhibitors and understanding the pathogenesis of depression and the mechanism of action of clinically effective antidepressants.
Preface; Neuroplasticity:: A New Approach to Treatment of Depression; Antidepressants Therapy & Risk of Suicide among Patients with Major Depressive Disorders; Monitoring of Antidepressant Therapy by Using Heart Rate Variability; The Overlap between Depression & Suicidal Behaviour:: Implication for the Preventative Effect of Antidepressant Pharmacotherapy; Synthetic Inhibitors of Prolyl Endopeptidase Exhibit Antidepressant-Like Effects in Rat Models of Depressive Syndrome & Anxiety-Depression State; Beyond the Monoamine Hypothesis:: The Quest for an Integrative Aetiology of Depression & New Therapeutic Strategies; Gender Differences in Response to Antidepressants; Neurogenesis & the Effect of Antidepressants; Index.
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