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Protein Tyrosine Phosphatases: Structure, Signaling and Drug Discovery

Protein Tyrosine Phosphatases: Structure, Signaling and Drug Discovery

9783110426434
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Description

- Tyrosine Phosphorylation in Cell Signaling: Discovery and Beyond
- Protein Tyrosine Phosphatase Super-Family of Proteins
- The PTP-Fold: Conserved Structure and Enzyme Mechanism
-The Bi-Domain RPTPs
- Modes of PTP Regulation Seen in Signaling
- Role of PTPs in Metabolism: PTP1B as the Prototype
- RPTPs in the Immune System: Special Role of CD45
- RPTPs in Axon Guidance
- Approaches to Study PTPs in Live Cells
- Role of PTPs in Host-Pathogen Interactions: Prokaryotic PTPs
- PTP Inhibitors in Drug Discovery: Conservative Approaches and New Frontiers

Product Details
De Gruyter
65289
9783110426434
9783110426434

Data sheet

Publication date
2018
Issue number
1
Cover
hard cover
Pages count
296
Dimensions (mm)
170.00 x 240.00
Weight (g)
693
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