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Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, Fifth Edition

Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, Fifth Edition

9781260288100
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Description


A simple, effective, and time-proven method of learning the essential concepts of pharmacology

A MUST-READ FOR THE USMLE STEP 2


Basic Concepts in Pharmacology:: What You Need to Know for Each Study Class, Fifth Edition provides you with a complete framework for studying – and understanding – the fundamental principles of drug actions.  This unique resource presents drugs by classes, details exactly what you need to know about each class, and reinforces key concepts and definitions.  With Basic Concepts in Pharmacology:: What You Need to Know for Each Study Class you will be able to identify your strengths and weaknesses, minimize memorization, streamline your study, and build your confidence.

With this innovative text youll be able to::
• Recognize the concepts you truly must know before moving on to other material
• Understand the fundamental principles of drug actions
• Organize and condense the drug information you must remember
• Review key information, which is conveniently presented in boxes, tables, and illustrations
• Identify the most important drugs in each class

Seven sections specifically designed to simplify the learning process and help you gain an understanding of the most important concepts::
• General Principles
• Drugs That Affect the Autonomic Nervous System
• Drugs That Affect the Cardiovascular System
• Drugs That Act on the Central Nervous System
• Chemotherapeutic Agents
• Drugs That Affect the Endocrine System
• Miscellaneous Drugs

If you are in need of a time-saving, stress-reducing approach to learning about drug classes and their mechanisms of action, your search ends here.

Product Details
60712
9781260288100
9781260288100

Data sheet

Publication date
2017
Issue number
5
Cover
paperback
Pages count
244
Dimensions (mm)
185 x 231
Weight (g)
410
  • 1. Where to Start
    Part I General Principles
    2. Receptor Theory
    Agonists
    Efficacy and Potency
    Therapeutic Index
    Antagonists
    Inverse Agonists
    3. Absorption, Distribution, and Clearance
    First-Pass Effect
    How Drugs Cross Membranes
    Bioavailability
    Total Body Clearance
    4. Pharmacokinetics
    Volume of Distribution
    First-Order Kinetics
    Zero-Order Kinetics
    Steady-State Concentration
    Time Needed to Reach Steady State
    Loading Dose
    5. Drug Metabolism and Renal Elimination
    Liver Metabolism
    Renal Excretion
    Part II Drugs That Affect the Autonomic Nervous System
    6. Review of the Autonomic Nervous System
    Why Include This Material?
    Relevant Anatomy
    Synthesis, Storage, Release, and Removal of Transmitters
    Receptors
    General Rules of Innervation
    Presynaptic Receptors
    7. Cholinergic Agonists
    Organization of Class
    Cholinergic Agonists
    Cholinesterase Inhibitors
    8. Cholinergic Antagonists
    Organization of Class
    Muscarinic Antagonists
    Ganglionic Blockers
    Neuromuscular Blockers
    9. Adrenergic Agonists
    Organization of Class
    Direct-Acting Agonists
    Dopamine
    Indirect-Acting Agents
    Cardiovascular Effects of Norepinephrine, Epinephrine, and Isoproterenol
    10. Adrenergic Antagonists
    Organization of Class
    Central Blockers
    ?-Blockers
    ß-Blockers
    Mixed ?- and ß-Blockers
    Part III Drugs That Affect the Cardiovascular System
    11. Antihypertensive Drugs
    Organization of Class
    Diuretics
    Drugs That Interfere With the Renin-Angiotensin System
    Angiotensin-Converting Enzyme Inhibitors
    Angiotensin II Receptor Blockers
    Selective Aldosterone Receptor Antagonists
    Direct Renin Inhibitor (DRI)
    Calcium Channel Blockers
    Nitrates
    Other Direct Vasodilators
    ?- and ß-Blockers
    Clonidine
    12. Drugs Used in Ischemic Heart Disease and Congestive Heart Failure
    Ischemic Heart Disease
    Congestive Heart Failure
    Reduction of Cardiac Workload
    Control of Excessive Fluid
    Enhancement of Contractility
    Cardiac Glycosides
    Sympathomimetics
    Phosphodiesterase Inhibitors
    Ranolazine
    13. Antiarrhythmic Drugs
    Organization of Class
    Class I Drugs (Sodium Channel Blockers)
    Class II Drugs (ß-Blockers)
    Class III Drugs (Potassium Channel Blockers)
    Class IV Drugs (Calcium Channel Blockers)
    Other Antiarrhythmic Drugs
    Drugs That Increase Heart Rate
    14. Drugs That Affect Blood
    Organization of Class
    Antiplatelet Agents
    Anticoagulants
    Thrombolytic Drugs
    Phosphodiesterase Inhibitors
    Drugs Used in the Treatment of Anemia
    15. Lipid-Lowering Drugs
    Organization of Class
    Additional Explanation of Mechanisms
    Part IV Drugs That Act on the Central Nervous System
    16. Drugs Used in Dementia
    Organization of Class
    Cholinesterase Inhibitors
    NMDA Blocker
    17. Anxiolytic and Hypnotic Drugs
    Tolerance and Dependence
    Organization of Class
    Barbiturates
    Benzodiazepines
    Buspirone
    Drugs for Insomnia
    Benzodiazepine Receptor Agonists
    Melatonin Receptor Agonist
    Orexin Recptor Antagonist
    18. Drugs Used in Mood Disorders
    Organization of Class
    Serotonin-Specific Reuptake Inhibitors
    Serotonin/Norepinephrine Reuptake Inhibitors
    Heterocyclics/TCAs
    Monoamine Oxidase Inhibitors
    Other Antidepressants
    Drugs Used in Bipolar Disorder
    19. Antipsychotics or Neuroleptics
    Organization of Class
    Typical Antipsychotics (First Generation)
    Serotonin-Dopamine Antagonists (Second Generation)
    Neuroleptic Malignant Syndrome
    20. Drugs Used in Parkinson Disease
    Organization of Class
    Dopamine Replacement Therapy
    Dopamine Agonist Therapy
    Anticholinergic Therapy
    21. Antiepileptic Drugs
    Organization of Class
    Important Details About the Most Important Drugs
    Other Drugs to Consider
    22. Narcotics (Opiates)
    Organization of Class
    Actions of Morphine and the Other Agonists
    Distinguishing Features of Some Agonists
    Opioid Antagonists
    Opioid Agonist-Antagonists
    23. General Anesthetics
    Organization of Class
    Uptake and Distribution of Inhalational Anesthetics
    Elimination of Inhalational Anesthetics
    Potency of General Anesthetics
    Specific Gases and Volatile Liquids
    Specific Intravenous Agents
    24. Local Anesthetics
    Organization of Class
    Mechanism of Action
    Special Features About Individual Agents
    Part V Chemotherapeutic Agents
    25. Introduction to Chemotherapy
    Approach to the Antimicrobials
    General Principles of Therapy
    Definitions
    Important Concepts to Understand
    Classification of Antimicrobials
    26. Inhibitors of Cell Wall Synthesis
    General Features
    ß-Lactams
    Penicillins
    Cephalosporins
    Carbapenems
    Monobactams (Aztreonam)
    Other Inhibitors of Cell Wall Synthesis
    Glycopeptides
    Bacitracin
    Fosfomycin
    Daptomycin
    27. Protein Synthesis Inhibitors
    General Features
    Aminoglycosides
    Tetracyclines
    Macrolides
    Streptogramins and Oxazolidinones
    Chloramphenicol
    Clindamycin
    28. Folate Antagonists
    Mechanism of Action
    Selected Features
    29. Quinolones and Urinary Tract Antiseptics
    Drugs in This Group
    Quinolones
    Methenamine
    30. Drugs Used in Tuberculosis and Leprosy
    Organization of Class
    Isoniazid
    Rifampin
    Pyrazinamide
    Ethambutol
    Dapsone
    31. Antifungal Drugs
    Organization of Class
    Azole Antifungals
    Polyene Antifungals
    Echinocandins
    Fungal Protein Inhibitors
    32. Anthelmintic Drugs
    Organization of Class
    Drugs Used Against Cestodes and Trematodes
    Drugs Used Against Nematodes
    Drugs Used Against Filaria
    33. Antiviral Drugs
    Organization of Class
    Anti-HIV Drugs
    Drugs Used in Influenza
    Drugs Used in Hepatitis B and C
    Other Antivirals
    34. Antiprotozoal Drugs
    Organization of Class
    Metronidazole
    Antimalarial Agents
    Therapeutic Considerations
    Special Features
    35. Anticancer Drugs
    Organization of Class
    Terminology and General Principles of Therapy
    Adverse Effects
    Cytotoxic Drugs
    Alkylating Agents
    Antimetabolites
    Antibiotics and Other Natural Products
    Antibodies
    Other Cytotoxic Drugs
    Hormonal Agents
    Signal Transduction Inhibitors
    Miscellaneous Agents
    Part VI Drugs That Affect the Endocrine System
    36. Adrenocortical Hormones
    Organization of Class
    Glucocorticoids
    Mineralocorticoids
    Inhibitors of Adrenocorticoid Synthesis
    37. Sex Steroids
    Organization of Class
    Estrogens
    Antiestrogens
    Progestins
    Antiprogestins
    Oral Contraceptives
    Androgens
    Antiandrogens
    GnRH Agonists and Antagonists
    PDE5 Inhibitors
    38. Thyroid and Parathyroid Drugs
    Organization of Class
    Thyroid Replacement Therapy
    Drugs That are Thyroid Downers
    Parathyroid Drugs
    39. Insulin, Glucagon, and Oral Hypoglycemic Drugs
    Organization of Class
    Insulins
    Oral Hypoglycemic Agents
    Part VII Miscellaneous Drugs
    40. Histamine and Antihistamines
    Organization of Class
    H1 Receptor Antagonists
    41. Respiratory Drugs
    Organization of Class
    ß-Agonists
    Leukotriene Modifiers
    Methylxanthines
    Cholinergic Antagonists
    Cromolyn and Omalizumab
    Pulmonary Hypertension
    Cystic Fibrosis
    42. Drugs That Affect the GI Tract
    Organization of Class
    Drugs That Act in the Upper GI Tract
    Drugs That Act in the Lower GI Tract
    Inflammatory Bowel Disease
    43. Nonnarcotic Analgesics and Anti-inflammatory Drugs
    Organization of Class
    Nonsteroidal Anti-Inflammatory Drugs
    COX-2 Inhibitors
    Salicylates, Including Aspirin
    Acetaminophen
    Other Drugs for Arthritis
    Antigout Agents
    Drugs Used in the Treatment of Headaches
    44. Immunosuppressives
    Organization of Class
    Calcineurin Inhibitors
    Mycophenolate Mofetil and Azathioprine
    Monoclonal Antibodies
    45. Drugs Used in Osteoporosis
    Organization of Class
    Bisphosphonates
    Denosumab
    Parathyroid Hormone
    Selective Estrogen Receptor Modulators
    Estrogens
    Calcitonin
    46. Toxicology and Poisoning
    Principles of Toxicology
    General Principles in the Treatment of Poisoning
    Specific Antidotes
    Index
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