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Goodman and Gilman's The Pharmacological Basis of Therapeutics, 12 Edition

9780071624428
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Description

The landmark text in medical pharmacology is now in full color

Includes DVD with image bank

A Doodys Core Title for 2017!

4 STAR DOODYS REVIEW!
This 12th edition of the most authoritative book in pharmacology is the best both in content and physical appearance....This edition of Goodman & Gilmans continues to be the most authoritative and widely used resource bridging the discipline of pharmacology with therapeutics. Moreover, readers will find this edition to be substantially improved from past editions in both content and physical appearance.--Doodys Review Service

The most universally respected and read medical text in all of pharmacology, Goodman & Gilmans The Pharmacological Basis of Therapeutics represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. Goodman & Gilmans careful balance of basic science and clinical application has guided thousands of practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing, and treating disease.

Enriched by a new full-color presentation and updated to reflect all critical new developments in drug action and drug-disease interaction, the twelfth edition includes more than 440 color illustrations depicting key principles and actions of specific pathways and therapeutic agents. The companion DVD includes all the images and tables in the text along with narrated animations.

Goodman & Gilmans The Pharmacological Basis of Therapeutics, 12e is divided into nine sections, covering::

  • General Principles
  • Neuropharmacology
  • Modulation of Cardiovascular Function
  • Inflammation, Immunomodulation, and Hematopoiesis
  • Endocrine Pharmacology
  • Gastrointestinal Pharmacology
  • Chemotherapy of Infectious Disease
  • Chemotherapy of Neoplastic Diseases
  • Special Systems Pharmacology

More than a textbook, Goodman & Gilmans is a working template for the effective and rational prescribing of drugs in daily practice.

Product Details
49194
9780071624428
9780071624428

Data sheet

Publication date
2011
Issue number
12
Pages count
1808
Dimensions (mm)
211 x 262
Weight (g)
3789
  • Contributors
    Consultants to the Editors
    Preface
    Preface to the First Edition
    SECTION I: GENERAL PRINCIPLES
    1. Drug Invention and the Pharmaceutical Industry, Suzanne M. Rivera and Alfred Goodman Gilman
    2. Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination, Iain L. O. Buxton and Leslie Z. Benet
    3. Pharmacodynamics: Molecular Mechanisms of Drug Action, Donald K. Blumenthal and James C. Garrison
    4. Drug Toxicity and Poisoning, Kevin C. Osterhoudt and Trevor M. Penning
    5. Membrane Transporters and Drug Response, Kathleen M. Giacomini and Yuichi Sugiyama
    6. Drug Metabolism, Frank J. Gonzalez, Michael Coughtrie, and Robert H. Tukey
    7. Pharmacogenetics, Mary V. Relling and Kathleen M. Giacomini
    SECTION II: NEUROPHARMACOLOGY
    8. Neurotransmission: The Autonomic and Somatic Motor Nervous Systems, Thomas C. Westfall and David P. Westfall
    9. Muscarinic Receptor Agonists, Joan Heller Brown and Nora Laiken
    10. Anticholinesterase Agents, Palmer Taylor
    11. Agents Acting at the Neuromuscular Junction and Autonomic Ganglia, Ryan E. Hibbs and Alexander C. Zambon
    12. Adrenergic Agonists and Antagonists, Thomas C. Westfall and David P. Westfall
    13. 5-Hydroxytryptamine (Serotonin) and Dopamine, Elaine Sanders-Bush and Lisa Hazelwood
    14. Neurotransmission and the Central Nervous System, Perry B. Molinoff
    15. Drug Therapy of Depression and Anxiety Disorders, James M. ODonnell and Richard C. Shelton
    16. Pharmacotherapy of Psychosis and Mania, Jonathan M. Meyer
    17. Hypnotics and Sedatives, S. John Mihic and r. Adron Harris
    18. Opioids, Analgesia, and Pain Management, Tony L. Yaksh and Mark S. Wallace
    19. General Anesthetics and Therapeutic Gases, Piyush M. Patel, Hemal H. Patel, and David M. Roth
    20. Local Anesthetics, William A. Catteral nad Kenneteh Mackie
    21. Pharmacotherapy of the Epilepsies, James O. McNamara
    22. Treatment of Central Nervous System Degenerative Disorders, David G. Standaert and Erik D. Roberson
    23. Ethanol and Methanol, Marc A. Schuckit
    24. Drug Addition, Charles P. OBrien
    SECTION III: MODULATION OF CARDIOVASCULAR FUNCTION
    25. Regulation of Renal Function and Vascular Volume, Robert F. Reilly and Edwin K. Jackson
    26. Renin and Angiotensin, Randa Hilal-Dandan
    27. Treatment of Myocardial Ischemia and Hypertension, Thomas Michel and Brian B. Hoffman
    28. Pharmacotherapy of Congestive Heart Failure, Bradley A. Maron and Thomas P. Rocco
    29. Anti-Arrhythmic Drugs, Kevin J. Sampson and Robert S. Kass
    30. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs, Jeffrey I. Weitz
    31. Drug Therapy for Hypercholesterolemia and Dyslipiedmia, Thomas P. Bersot
    SECTION IV: INFLAMMATION, IMMUNOMODULATION, AND HEMATOPOIESIS
    32. Histamine, Bradykinin, and Their Antagonists, Randal A. Skidgel, Allen P. Kaplan, and Ervin G. Erdös
    33. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor, Emer M. Smyth, Tilo Grosser, and Garret A. Fitzgerald
    34. Anti-inflammatory, Antipyretic, and Analgesic Agents; Pharmacology of Gout, Tilo Grosser, Emer Smyth, and Garret A. FitzGerald
    35. Immunosupressants, Tolerogens, and Immunostimulants, Alan M. Krensky, William M. Bennett, and Flavio Vincenti
    36. Pulmonary Pharmacology, Peter J. Barnes
    37. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins, Kenneth Kaushansky and Thomas J. Kipps
    SECTION V: HORMONES AND HORMONE ANTAGONISTS
    38. Introduction to Endocrinology: The Hypothalamic-Pituitary Axis, Keith L. Parker and Bernard P. Schimmer
    39. Thyroid and Anti-Thyroid Drugs, Gregory A. Brent and Ronald J. Koenig
    40. Estrogens and Progestins, Ellis R. Levin and Stephen R. Hammes
    41. Androgens, Peter J. Snyder
    42. ACTH, Adrenal Steroids, and Pharmacology of the Adrenal Cortex, Bernard P. Schimmer and John W. Funder
    43. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia, Alvin C. Powers and David DAlessio
    44. Agents Affecting Mineral Ion Homeostatis and Bone Turnover, Peter A. Friedman
    SECTION VI: DRUGS AFFECTING GASTROINTESTINAL FUNCTION
    45. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease, John L. Wallace and Keith A. Sharkey
    46. Treatment of Disorders of Bowel Motility and Water Flux: Anti-Emetics; Agents Used in Biliary and Pancreative Disease, Keith A. Sharkey and John L. Wallace
    47. Pharmacotherapy of Inflammatory Bowel Disease, John L. Wallace and Keith A. Sharkey
    SECTION VII: CHEMOTHERAPY OF MICROBIAL DISEASES
    48. General Principles of Antimicrobial Therapy, Tawanda Gumbo
    49. Chemotherapy of Malaria, Joseph M. Vinetz, Jerome Clain, Viengngeun Bounkeua, Richard T. Eastman, and David Fidock
    50. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections, Margaret A. Phillips, Samuel L. Stanley, Jr.
    51. Chemotherapy of Helminth Infections, James McCarthy, Alex Loukas, and Peter J. Hotez
    52. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections, William A. Petri, Jr.
    53. Penicillins, Cephalosporins, and Other ß-Lactam Antibiotics, William A. Petri, Jr.
    54. Aminoglycosides, Conan MacDougall and Henry F. Chambers
    55. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents, Conan MacDougall and Henry F. Chambers
    56. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy, Tawanda Gumbo
    57. Antifungal Agents, John E. Bennett
    58. Antiviral Agents (Nonretroviral), Edward P. Acosta and Charles Flexner
    59. Antiretroviral Agents and Treatment of HIV Infection, Charles Flexner
    SECTION VIII: CHEMOTHERAPY OF NEOPLASTIC DISEASES
    60. General Principles of Cancer Chemotherapy, Bruce A. Chabner
    61. Cytotoxic Agents, Bruce A. Chabner, Joseph Bertino, James Cleary, Taylor Ortiz, Andrew Lane, Jeffrey G. Supko, and David Ryan
    62. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines, Bruce A. Chabner, Jeffrey Barnes, Joel Neal, Erin Olson, Hamza Mujagic, Lecia Sequist, Wynham Wilson, Dan L. Longo, Constantine Mitsiades, and Paul Richardson
    63. Natural Products in Cancer Chemotherapy: Hormones and Related Agents, Beverly Moy, Paul Goss, Richard J. Lee, and Matthew Smith
    SECTION IX: OPHTHALMOLOGY
    64. Ocular Pharmacology, Jeffrey D. Henderer and Christopher J. Rapuano
    65. Dermatological Pharmacology, Craig Burkhart, Dean Morrell, and Lowell Goldsmith
    66. Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders, Bernard P. Schimmer and Keith L. Parker
    67. Environmental Toxicology: Carcinogens and Heavy Metals, Michael C. Byrns and Trevor M. Penning
    APPENDICES
    I. Principles of Prescription Order Writing and Patient Compliance, Iain L.O. Buxton
    II. Design and Optimization of Dosage Regimens: Pharmacokinetic Data, Kenneth E. Thummel, Danny D. Shen, and Nina Isoherranen
    Index
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