Cleft Lip and Palate

From Origin to Treatment

Authors:

Diego F. Wyszynski

Brand: OUP USA

ISBN: 9780195139068

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Description

Major advances in the diagnosis and treatment of oral clefts have been made in the past 50 years, and recent genetics and epidemiological studies have led to new theories about the causes of cleft lip and palate. Addressing issues that are relevant to clinicians, researchers and family members, this book is a comprehensive, well-illustrated, and up-to-date account of the many facets of this common disorder. The authors describe the embryological and molecular mechanisms of cleftcausation, present and illustrate the genetic and epidemiological methods used to identify risk factors for oral clefts, and describe treatments by the various professionals of the cleft team. A section is also devoted to the integration of research findings into public health practice, includingethical and financial considerations. The book draws together such diverse disciplines as craniofacial development, gene mapping, epidemiology, medicine, ethics, health economics, and health policy and management, and it will be an invaluable reference work.

Product Details

Brand OUP USA

Reference 85994

EAN13 9780195139068

ISBN 9780195139068

Data sheet

Publication date: 2002
Issue number: 1
Cover: hard cover
Pages count: 518
Dimensions (mm): 229 x 286
Weight (g): 2378

Foreword; Section I - Basic Principles; Part I - Basic Embryology of Cleft Lip and Palate; Formation of the Primary Palate; Palatogenesis:: Closure of the Secondary Palate; Genes Implicated in Lip and Palate Development; Part II - Clinical Features of Cleft Lip and Cleft Palate; The Orofacial Examination:: Normal and Abnormal Findings; Classification and Description of Nonsyndromic Clefts; Syndromes with Orofacial Clefting; Morphometric Characteristics of Subjects with Oral Facial Clefts and Their Relatives; Craniofacial Morphology and Growth in Infants and Young Children with Cleft Lip and Palate; Part III - Epidemiology of Cleft Lip and Palate; Methodological Issues in Epidemiological Studies of Oral Clefts; Exposure Assessment in Studies of Oral Clefts; Birth Defects Surveillance Systems and Oral Clefts; Epidemiology of Oral Clefts:: An International Perspective; Environmental Risk Factors and Oral Clefts; Maternal Nutrition and Oral Clefts; Experimental Models for the Study of Oral Clefts; Part IV - Genetics of Cleft Lip and Palate; The Human Genome Project; Twin Studies in Oral Clefts Research; Segregation Analyses; Mode of Inheritance of Oral Clefts; Associate Studies; Locating Genes for Oral Clefts in Humans; Mapping Studies in Animal Models; Gene-Environment Interaction and Risk to Oral Clefts; Section II - Treatment; Developing a Cleft Palate or Craniofacial Team; Health Care for Children with Cleft Lip and Palate:: Comprehensive Services and Infant Feeding; The Staging of Cleft Lip and Palate Reconstruction:: Infancy through Adolescence; Evaluation and Management of Speech, Language, and Articulation Disorders; Pediatric Dental Care; The Role of the Orthodontist in the Management of Patients with Cleft Lip and/or Palate; Otolaryngologic Needs of Individuals with Oral Clefts; Genetic Counseling and Interpretation of Risk Figures; Psychological Care of Children with Cleft Lip and Palate in the Family; International Surgical Missions; Evidence-Based Care for Children with Cleft Lip and Palate; Section III - Public Health Issues; Prevention of Oral Clefts Through the Use of Folic Acid and Multivitamin Supplements:: Evidence and Gaps; Costs of Cleft Lip and Palate:: Personal and Societal Implications; Insurance and Coverage of Care; Parents Perspective on Cleft Lip and Palate; Ethical Issues in the Care of Children with Craniofacial Conditions; Translating Research Findings into Public Health Action and Policy; Educating the Practitioner and the Public; Innovations in International Cooperation for Patients with Cleft Lip and Palate; Appendix:: Directory of Internet Resources;