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Basic Science of Spinal Diseases
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This book is a comprehensive guide to the basic science of spinal diseases for trainees and clinicians. Divided into four sections, the authors begin with detailed discussion on the anatomy, physiology and pathophysiology of the intervertebral disc. The following sections examine the science of spinal instrumentation and spinal interventions.
Clinical chapters are structured in a uniform format, beginning with the presentation of a clinical case, followed by detailed discussion and supporting evidence. Each case ends with challenging questions to direct further investigation.
This book is a highly useful compilation of research work from recognised surgeons from the USA and The Netherlands, specialising in the fields of physiology, biology, biomechanics and mechanobiology.
Key points
- Comprehensive guide to the basic science of spinal diseases
- Based on research work of specialists in physiology, biology, biomechanics and mechanobiology
- US and Dutch author and editor team
- Includes nearly 240 full colour images and illustrations
Data sheet
- Publication date
- 2013
- Issue number
- 1
- Cover
- hard cover
- Pages count
- 300
- Dimensions (mm)
- 216.00 x 279.00
- Weight (g)
- 650
Section 1:: Anatomy and Physiology of the Intervertebral Disc
- Anatomy and Structure of the Intervertebral Disc
- Biomechanics of Intervertebral Disc
- Vascular Anatomy of the Endplates and Nutrient Supply of the Disc
- Muscular Anatomy of the Spine
- Imaging of the Intervertebral Disc
- Animal Models for Disc Degeneration
- Animal Models of Back Pain and Sciatica
- Animal Models for Spinal Deformity and their Role in the Development of Surgical Nonfusion AIS Treatments
Section 2:: Pathophysiology of the Intervertebral Disc
- Pathophysiology of Disc Degeneration
- Genetics of Disc Degeneration
- The Role of Inflammation in Disc Degeneration
- Understanding the Pathways of Pain
- Treatment Strategies to Regenerate the IVD
Section 3:: The Science of Spinal Instrumentation
- Implant Properties of Spinal Instrumentation
- Biomechanics of Spinal Instrumentation
- Biomechanics of Cervical Spine Instrumentation
- Biomechanics of Thoracolumbar Instrumentation
- Biomechanics of Lumbar Interbody Fusion
- Biomechanics of Motion-Preserving Implants
- Biomechanics of Interspinous Process Devices
- Biomechanics of Cement Augmentation
- Implant Design and Testing
- Navigating the Regulatory and Reimbursement Pathways
- The Patent Process
Section 4:: The Science of Spinal Interventions
- Pharmaceutical Management of Spine Pain
- Biochemistry of Epidural Steroid Injections
- Basic Science of Discography and Provocative Testing
- The Use of Stem Cells in Spine Surgery
- Biology of Spinal Fusion
- Bone Graft Extenders
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