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Based on the Second Edition of Marks Basic Medical Biochemistry:: A Clinical Approach, Marks Essentials of Medical Biochemistry has been streamlined to focus on only the most essential biochemical concepts important to medical students. The authors present facts and pathways to emphasize how the underlying biochemistry is related to the bodys overall physiological functions. This text presents patients to the students as the biochemistry is being discussed, which strengthens the link between biochemistry and medicine and allows the student to learn about this interaction as the biochemistry is presented. Each chapter includes clinical and biochemical notes and comments, questions and answers to encourage further thinking, and suggested references for those who would like to pursue a particular topic in more depth.
Data sheet
FUEL METABOLISM
An Overview of Fuel Metabolism
CHEMICAL AND BIOLOGICAL FOUNDATIONS OF BIOCHEMISTRY
Water, Acids, Bases, and Buffers
Structures of the Major Compounds of the Body
Amino Acids in Proteins
Structure-Function Relationships in Proteins
Enzymes as Catalysts
Regulation of Enzymes
Cell Structure and Signaling by Chemical Messengers
GENE EXPRESSION AND PROTEIN SYNTHESIS
Structure of the Nucleic Acids
Synthesis of DNA
Transcription:: Synthesis of RNA
Translation:: Synthesis of Proteins
Regulation of Gene Expression
Use of Recombinant DNA Techniques in Medicine
OXIDATIVE METABOLISM AND THE GENERATION OF ATP
Cellular Bioenergetics:: ATP and O2
Tricarboxylic Acid Cycle
Oxidative Phosphorylation, Mitochondrial Function, and Oxygen Radicals
Generation of ATP from Glucose:: Glycolysis
Oxidation of Fatty Acids and Ketone Bodies
CARBOHYDRATE METABOLISM
Basic Concepts in the Regulation of Fuel Metabolism by Insulin, Glucagons and Other Hormones
Digestion, Absorption, and Transport of Carbohydrates
Formation and Degradation of Glycogen
Pathways of Sugar Metabolism:: Pentose Phosphate Pathway, Fructose and Galactose Metabolism
Synthesis of Glycosides, Lactose, Glycoproteins, and Glycolipids
Gluconeogenesis and Maintenance of Blood Glucose Levels
LIPID METABOLISM
Digestion and Transport of Dietary Lipids
Synthesis of Fatty Acids, Triacylglycerols, and the Major Membrane Lipids
Cholesterol Absorption, Synthesis, Metabolism and Fate
Integration of Carbohydrate and Lipid Metabolism
NITROGEN METABOLISM
Protein Digestion and Amino Acid Absorption
Fate of Amino Acid Nitrogen:: Urea Cycle
Synthesis and Degradation of Amino Acids
Tetrahydrofolate, Vitamin B12, and S-Adenosylmethionine
Purine and Pyrimidine Metabolism
Intertissue Relationships in the Metabolism of Amino Acids