Second Primary Cancers in Cancer Survivors

Cancer remains a major global health challenge and the second leading cause of death worldwide. Advances in therapy, early diagnosis, and screening have improved survival rates, leading to an increase in second primary cancers—new cancers that develop months or years after initial diagnosis and treatment. The rate of second primary cancers varies among different cancer types and has been steadily rising over recent decades. Factors such as predisposing genetics and treatments for primary cancers can increase the risk. As cancer survivors live longer, understanding secondary malignancies is essential for optimizing follow-up care and improving long-term outcomes. This book provides comprehensive insights into the epidemiology, risk factors, and management of second primary cancers in survivors.