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Chronic Myeloid Leukemia: From Daily Management to Complicated Issues
9781629489711
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Description
Targeted therapy has revolutionised modern oncology practice and has completely changed the outcome of once universally fatal diseases like chronic myeloid leukaemia (CML). The last decade has witnessed significant advances in the management of CML, which has become more like a chronic disease. Written by experts in the field, this volume nicely describes the current knowledge of the pathophysiology, clinical features, and management of CML. It covers not only clinical topics but also the basic science underlying these practices. It will be of help to clinicians and basic scientists alike. In addition to the state of the art treatment of CML, this book also covers many uncommon but very important special topics like management of CML in pregnancy or with children, management of resistance to new tyrosine kinases and treatment of the advanced phase of the disease. Written to be easily digestible, patients will also be able to access important and universally useful information on CML (eg:: diagnosis, symptoms and signs, and treatment). Some themes especially, including drug and food interactions of tyrosine kinase inhibitors (TKIs), CML treatment during pregnancy, advantages/disadvantages of the most commonly used TKIs, and bone marrow transplantation indications, will be of popular concern. This extensively referenced book therefore should be of great help to both novices and experts in the field.
Product Details
74476
9781629489711
9781629489711
Data sheet
- Publication date
- 2014
- Issue number
- 1
- Cover
- hard cover
- Pages count
- 382
- Dimensions (mm)
- 180.00 x 260.00
- Weight (g)
- 810
- Definition, Epidemiology, Natural History & Clinical Phases; CML:: Clinical Diagnosis, Differential Diagnosis & Scoring Systems; Chronic Myelogenous Leukemia, Morphology & Immunophenotype; Cytogenetic & Molecular Aspects of CML; Molecular Mechanisms in CML Pathogenesis; Secondary Resistance to Tyrosine Kinase Inhibitors:: Focus on Molecular Mechanisms other than BCR-ABL Overexpression & Mutations; Frontline Therapy; Management of Tyrosine Kinase Inhibitors Resistance; Management of Chronic Myeloid Leukemia (CML):: Accelerated Phase (AP); Management of Chronic Myeloid Leukemia (CML):: Blast Phase (BP); Hematopoietic Cell Transplant for CML; Summary of Treatment & Recommended Follow-Up of CML Patients; CML in Pediatric Population; Blastic Transformation in Extramedullary Sites; Managing CML in Pregnancy; Drug & Food Interactions with TKIs; Molecular Monitoring of CML:: Role for Novel Markers Additional to BCR-ABL; Can We Cure CML without Transplantation?; Future Directions.
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