Although there have been tremendous progress in cancer research and treatment, the mortality caused by this disease is still very high. Cancer is the leading cause of death worldwide and second leading cause of death in the United States of America. The book covers topics including the role of various signalling pathway in development, regulation of cell fate, tumour angiogenesis, duodenal neoplasias, breast, colorectal and prostate cancer, cancer development and progression, microRNA in cancer and epigenetic regulation of cancer. This book will provide valuable information for cell biologists, geneticists, cancer biologists, clinicians, and students involved in various aspects of cell signalling, regulation of genes and cancer.
Preface; Cell Death & Survival Signaling in Cancer Therapy; C4ST-1 & Chondroitin Sulfate in Growth Factor Signaling, Development, & Cancer; NFAT Signaling & Transcription in Cancer Development & Progression; JAK/STAT Signaling in Cell Fate & Tumorigenesis; Role of TGF ß & Regulatory T Cells in Prostate Cancer; Signaling Pathways, Gene Regulation & Duodenal Neoplasias; Targeting Cancer Cells in Head & Neck Tumors; AKT in Human Colorectal Cancer.
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