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Field Cancerization: Basic Science & Clinical Applications

Field Cancerization: Basic Science & Clinical Applications

9781617610066
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Description
The presence of multiple cancers in one patient has excited the interest of many investigators, and considerable literature has accumulated on this subject. The scientific concepts and clinical importance of field cancerization are the subject matter of this book. This book is a compendium of importance to oncologists and cancer researchers and caregivers. Existent knowledge on cancer biology and therapy has been vastly expanded by this concept of cancer evolution. Expanding super-competitors, multi-step carcinogenesis, and stem cell theories are some novel mechanistic models of carcinogenesis discussed in this book. Extensively covered in this book as well, are the cellular and molecular changes representative of field cancerisation in several cancers, including haematologic and paediatric cancers.
Product Details
Nova Science Publishers Inc
73553
9781617610066
9781617610066

Data sheet

Publication date
2011
Issue number
1
Cover
hard cover
Pages count
605
Dimensions (mm)
260.00 x 180.00
Weight (g)
1276
  • Preface; Expanding Supercompetitors as Mechanism of Field Cancerization; The Multistep Field Cancerization Theory of Carcinogenesis; Development of Tumor Stem Cells:: Implication in Field Cancerization; Epidemiology of Synchronous & Metachronous Type Multiple Primary Neoplasms; Field Cancerization in Derivatives of the Embryonic Foregut:: An Observation Based on Epidemiological Patterns; Field Cancerization & Oral Leukoplakia; Field Cancerization in Head & Neck Squamous Cell Carcinoma with Focus on Second Primary Tumors; Field Cancerization in Esophageal Epithelia Demonstrated by Telomere Shortening & Chromosomal Instability; Field Cancerization in Mammary Tissues; Field Cancerization in Gastric Cancer; Field Cancerization in Colorectal Cancer; Epigenetic Changes in Hepatic Tissues:: Evidence of Field Cancerization; Molecular Genetic Alterations in Preneoplastic And Neoplastic Lesions Of the Gallbladder; Field Cancerization in Intraductal Papillary Mucinous Neoplasia of the Pancreas; Field Cancerization iIn Urothelial Carcinomas of the Upper Urinary Tract; Clonality of Multifocal Urothelial Cancer & Field Cancerization; Evidence of Skin Field Cancerization; Management of Field Cancerization:: The Case of Actinic Keratosis; Field Cancerization in Endometrial Carcinoma; Field Cancerization in Vulvar, Vaginal & Cervical Epithelia; Molecular Signatures in Ovarian Cancer; Epigenetic Changes in Prostatic Tissues:: Evidence of Field Cancerization; Epigenetic Field Changes in Pediatric Cancers; Epigenetics in Hematological Malignancies; Molecular Signatures as Cancer Biomarkers:: Methodologic Issues in Discovery, Validation, Qualification, & Standardization; Chemoprevention Targeting Epigenetic Changes in Cancer; Index.
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