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Acute Lymphoblastic Leukemia: Etiology, Pathogenesis and Treatments

Acute Lymphoblastic Leukemia: Etiology, Pathogenesis and Treatments

9781614708728
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Description
Acute lymphoblastic leukaemia (ALL) is a malignant disorder of the bone marrow in which a lymphoid precursor cell becomes genetically altered resulting in dysregulated proliferation and clonal expansion of neoplastic cells. It is the most common malignancy in children, representing nearly one third of all paediatric cancers. In this book, the authors present topical research in the study of acute lymphoblastic leukaemia including genome wide association studies in paediatric acute lymphoblastic leukaemia; mice deficient for the Slp65 signalling protein which is a model for ALL; histone deacetylase inhibitors and maintenance therapy in Ph negative adult acute lymphoblastic leukaemia.
Product Details
Nova Science Publishers Inc
73369
9781614708728
9781614708728

Data sheet

Publication date
2012
Issue number
1
Cover
hard cover
Pages count
237
Weight (g)
736
  • Preface; Genome Wide Association Studies in Pediatric Acute Lymphoblastic Leukemia:: Pathogenesis & Therapy; Mice Deficient for the Slp65 Signaling Protein:: A Model for Pre-B Cell Acute Lymphoblastic Leukemia; Childhood Acute Lymphoblastic Leukemia; Systems Approaches to Childhood Leukemogenesis; Histone Deacetylase Inhibitors:: Pre-Clinical & Clinical Evidence in Treating Acute Lymphoblastic Leukemia; A Therapeutic Target in Leukemia:: The NK-1 Receptor; Minimal Residual Disease Monitoring in Childhood Acute Lymphoblastic Leukemia; Clinical Relevance & Application of Cytogenetic Approaches in Pediatric Acute Lymphoblastic Leukaemia; Maintenance Therapy in Ph Negative Adult Acute Lymphoblastic Leukemia; The Role of Innate & Adaptive Immunity in Childhood Acute Lymphoblastic Leukemia; Index.
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