Melanomas are usually highly proliferative, invasive and are most frequently metastatic. Melanoma accounts for nearly 4% of skin cancer cases but, because of its highly metastatic capability, for 74% of all skin cancer mortalities. Therefore, melanoma is one of the deadliest forms of cancer and its treatment continues to be challenging. This book presents topical research in the study of the symptoms, diagnoses and treatment of metastatic melanoma. Topics discussed include new therapeutic alternatives for melanoma; the metastatic cascade and experimental treatments; pediatric melanoma and the relative risk of metastatic melanoma.
Preface; Experimental Treatments for Blocking Melanoma Metastasis; Invasion & Metastasis:: Major Obstacles to Curative Cancer Therapy; Metastatic Melanoma in the Paediatric Age; The Role of Sentinel Lymph Node Biopsy in Patients with Thick (Breslow=4mm) Cutaneous Melanoma; Hormone Replacement Therapy & Malignant Melanoma; New Attempts for Treating Stage III-N1 Melanoma Patients; Novel Diagnostic & Prognostic Biomarkers & Molecular Therapeutic Targets in Aggressive, Metastatic & Recurrent Melanomas; Melanoma Inhibitory Activity (MIA) as a Serological Marker in Metastatic Uveal Melanoma; Index.
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