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Role of Prostate-Specific Antigen (PSA) in Pathological Angiogenesis & Prostate Tumor Growth
9781611229752
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Description
Prostate specific antigen (PSA) is a serine protease present in an enzymatically inactive form in human serum at a concentration of nanograms/ml; serum PSA (S-PSA) is used widely as a surrogate marker in the diagnosis and management of prostate cancer (CaP). However, the vast majority of PSA produced in the prostate is secreted as active enzyme into the seminal fluid or is sequestered within the prostate tissue microenvironment. This book examines the role of the prostate-specific antigen in prostate tumour growth.
Product Details
73160
9781611229752
9781611229752
Data sheet
- Publication date
- 2012
- Issue number
- 1
- Cover
- paperback
- Dimensions (mm)
- 230.00 x 155.00
- Weight (g)
- 114
- Prostate Cancer Statistics; Biology of PSA & Regulation by Androgen; PSA in blood; PSA screening & early detection of CaP; Angiogenic Growth Factors & Cytokines Associated with CaP Growth, Metastasis & Invasion; Role of PSA in CaP Angiogenesis; Isolation & characterization of human PSA for evaluation of the physiological role of PSA in angiogenesis; Purification & Characterization of f-PSA from Seminal Plasma; Role of f-PSA in angiogenesis & prostate tumor growth; Role of PSA in angiogenesis by endothelial cells in vitro; Effect of Treatment of CaP cells (PC-3M) with f-PSA on the Differential Expression of Proteins; Conclusion; Index.
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