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New Quinolones with Potential Anti-MRSA Activity

New Quinolones with Potential Anti-MRSA Activity

9781608767366
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Description
Quinolone antibacterial agents are among the most attractive drugs in the field of anti-infective chemotherapy. Quinolones target the essential bacterial type II topoisomerases, which are involved in DNA replication and metabolism. Despite a large number of quinolones approved for the treatment of bacterial infections, there have been progressive efforts for the discovery of new quinolones to overcome the problem of growing bacterial resistance. This book discusses the structural requirements of quinolones for anti-MRSA activity and introduce the newly developed quinolones to manage MRSA infections, their in-vitro effectiveness based on recent studies and structure-activity relationships.
Product Details
Nova Science Publishers Inc
73056
9781608767366
9781608767366

Data sheet

Publication date
2010
Issue number
1
Cover
paperback
Pages count
110
Dimensions (mm)
230.00 x 155.00
Weight (g)
218
  • Introduction; History of Quinolones Development; Mechanism of Action; Mechanisms of quinolone resistance in S. aureus; General Structural Features (Structure-Activity Relationships); Newer Quinolones with Potential Anti-MRSA Activity; Conclusion; Index.
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