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Aromatase Inhibitors: Types, Mode of Action & Indications

Aromatase Inhibitors: Types, Mode of Action & Indications

9781607417118
592.14 zł
532.92 zł Save 59.22 zł Tax included
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Description
Aromatase inhibitors (AI) are a class of drugs used in the treatment of breast cancer and ovarian cancer in postmenopausal women. Aromatase is an enzyme that synthesises oestrogen and aromatase inhibitors block the synthesis of oestrogen, which is needed in some cancers to grow. As breast tissue is stimulated by estrogens, decreasing their production is a way of suppressing recurrence of the breast tumour tissue. In contrast to pre-menopausal women, in whom most of the oestrogen is produced in the ovaries, in post-menopausal women most of the bodys oestrogen is produced in the adrenal gland from the conversion of androgens. Investigations are ongoing to look for other applications and researchers continue to study aromatase inhibitors as a way to stimulate ovulation or suppress oestrogen production in endometriosis. This book presents the latest research from around the world in this dynamic field.
Product Details
Nova Science Publishers Inc
72899
9781607417118
9781607417118

Data sheet

Publication date
2010
Issue number
1
Cover
hard cover
Pages count
189
Dimensions (mm)
260.00 x 180.00
Weight (g)
532
  • Preface; Anti-Estrogen Agents:: Aromatase Inhibitors; Past, Present and Future; Aromatase Inhibitors:: Types, Mode of Action and Indications; Aromatase Inhibitors; Upfront vs. Sequential Aromatase Inhibitors:: An Ongoing or Settled Debate?; Aromatase Expression in the Endometrium and its Role in the Development of Uterine Pathology; Aromatase Inhibitors for the Medical Treatment of Endometriosis; An Update of the Use of Aromatase Inhibitors in the Management of Breast Cancer; Aromatase Inhibitors in Ovulation Induction:: Myth or Reality?; The Use of Aromatase Inhibitors in Ovarian Cancer and Identification of Responsive Tumours; Index.
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