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Holland-Frei Cancer Medicine 8

Holland-Frei Cancer Medicine 8

9781607950141
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Description
The consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists and others who treat cancer patients, Cancer Medicine 8 covers the ever-widening sphere of current cancer knowledge and clinical practice.

In this new 8th edition an outstanding editorial team from world-renowned medical centers continues to hone the leading edge forged in previous editions, with timely information on biology, immunology, etiology, epidemiology, prevention, screening, pathology, imaging and therapy.

The book is a testament to the editorial panels creed that innovative, comprehensive, multidisciplinary treatment of cancer patients must be grounded in a fundamental understanding of cancer biology. Cancer Medicine 8 does a superb job of bringing scientific principles into clinical practice. This text is the ultimate resource of new information providing the basis for better informed cancer therapy choices.

Cancer Medicine 8 features hundreds of 4-color illustrations, photographs, tables, graphs and algorithms that make this text an invaluable clinical tool in recognizing characteristic appearances of both patient and tissue.

The 137 tightly focused chapters are organized into 5 sections::

I:: Cardinal Manifestations of Cancer
II:: Scientific Foundations of Cancer
III:: Principles of Cancer Diagnosis
IV:: Principles of Therapeutic Modalities
V:: Principles of Multidisciplinary Management

Major Revisions::

Chapter 6:: Oncogenes An entire section is devoted to oncogenes like kit, Ret, Braf, Akt genes and the new drugs that specifically target them. This chapter not only provides a list of these new therapies but also insight as to how they target the oncogenes and their mutations, as well as therapy response and efficacy.
Chapter 11:: Tumor Angiogenesis This chapter provides a wealth of new data and understanding of the mechanisms of angiogenesis and how it contributes to the malignancy of various cancers The Clinical Advancement section provides an extensive summary of new trials investigating numerous novel angiogenesis agents
Chapter 33:: Chemoprevention This chapter also provides a considerable amount of new information for a broad range of clinical trials such as the HPV vaccine trial Future, Select, Star, Approve and PreSAP. The rationales for these trials are discussed and resulting data from the completed trials are presented.
Chapter 55:: Cytokines Research on cytokines is another area that is exploding in magnitude. This chapter presents a wealth of new information on promising new therapeutic agents.There is also updated information on the therapeutic usage of currently available agents such as hemotopoietic growth factors (HGF), erythropoietin and thromobopoietic agents.
Chapter 56:: Monoclonal Serotherapy A considerable amount of research has been done in the past few years on therapeutic and targeted agents in cancer therapy. Updated information and data is provided from recent trials for therapies previously discussed in Cancer Medicine edition 7 covering therapeutic agents and targeted toxins.
Chapter 77:: Neoplasms of the Head and Neck There is a discussion of changes in treatment methods for certain cancers such as the recent shift from surgery to combined chemotherapy with radiotherapy for tonsillar cancer, nasal and paranasal sinuses cancers and laryngeal cancer.
Chapter 78:: Lung Cancer Advances in diagnostic techniques are described such as ultrasound-guided fine needle aspiration or electromagnetic navigation diagnostic bronchoscopy. Video assisted thoracoscopic surgery (VATS) discussion is updated. New sections are devoted to prognostic and predictive biomarkers.

Product Details
46982
9781607950141
9781607950141

Data sheet

Publication date
2010
Issue number
8
Cover
hard cover
Pages count
2048
Dimensions (mm)
225 x 287
Weight (g)
5

  • PART I: CARDINAL MANIFESTATIONS OF CANCER

    1: Cardinal Manifestations of Cancer James F. Holland, Emil Frei, III, Waun Ki Hong, Donald Kufe, Robert Bast, William Hait, Raphael Pollock, Ralph Weichselbaum

    PART II: SCIENTIFIC FOUNDATIONS OF CANCER

    SECTION 1: CANCER BIOLOGY

    2: Molecular Biology, Genomics, and Proteomic, and Mouse Models of Human Cancer Kornelia Polyak, Matthew Meyerson, William Hahn, David Tuveson
    3: Cell Proliferation and Differentiation Michael Andreeff, David W. Goodrich, H. Phillip Koeffler
    4: Apoptosis and Cancer John Reed
    5: Growth Factors and Signal Transduction in Cancer Stuart A. Aaronson, Luca Grumolato
    6: Oncogenes Marco A. Pierotti, Milo Frattini, Gabriella Sozzi, Carlo M. Croce
    7: Tumor Supressor Genes Gen-Ho Park, Bert Vogelstein, David Cosgrove
    8: Genomic Alterations and Chromosomal Abberations in Human Cancer Jeff Trent, Kevin M. Brown, Jonathan J. Keats, Aleksandar Sekulic, Cheryl L. Willman
    9: Biochemistry of Cancer Raymond W. Ruddon, Donald W. Kufe
    10: Invasion and Metastases Elise C. Kohn
    11: Tumor Angiogenesis John Heymach, Judah Folkman, Raghu Kalluri
    12: Epigenetics (to include Novel Treatment) Steve Baylin

    SECTION 2: CANCER IMMUNOLOGY

    13: Cancer Immunotherapy Karl S Peggs, Sergio A Quezada, Padmanee Sharma, James P Allison

    SECTION 3: CANCER ETIOLOGY

    14: Genetic Predisposition to Cancer Henry T. Lynch, Vadana Gupta, Marcia S. Brose
    15: Chemical Carcinogenesis Ainsley Weston, Curtis C. Harris
    16: Hormones and the Etiology of CancerLeslie Bernstein, C. Leigh Pearce, Iona Cheng, Katherine DeLellis Henderson
    17: Ionizing Radiation David J. Grdina
    18: Ultraviolet Radiation CarcinogenesisJames E. Cleaver, David L. Mitchell
    19: Inflammation, Trauma and Physical Agents in Cancer Debbie Laskin
    20: RNA Tumor Viruses, Robert Gallo, Marvin S. Reitz
    21: Herpesviruses Jeffrey I. Cohen
    22: Papillomaviruses and Cervical Neoplasia Christopher P. Crum, Catherine McLachlin
    23: Hepatitis Viruses Max W. Sung, Swan N. Thung
    24: Parasites Piero Mustacchi

    SECTION 4: TRANSLATIONAL CANCER MEDICINE

    25: Molecular Imaging Juri Gerlovani
    26: Molecular Diagnostics in Cancer Bryan T. Hennessy, Robert C. Bast, Jr., Gordon B. Mills
    27: Personalized Medicine in Oncology Drug Development William N. Hait, Nicolas Dracopoli, Steve Heller, Chris H. Takimoto
    28: Genomic and Systems Biology Joseph W. Gray
    29: Cancer Nanotechnology Mauro Ferrari

    SECTION 5: CANCER EPIDEMIOLOGY, PREVENTION and SCREENING

    30: Cancer Epidemiology Michael J. Thun
    31: Prevention of Tobacco-Related Products Steve Hecht, Dorothy Hatsukami
    32: Nutrition in the Etiology and Prevention of Cancer Steven K. Clinton
    33: Chemoprevention of Cancer Scott M. Lippman, Waun Ki Hong
    34: Cancer Screening and Early Detection Robert A. Smith, Stephen W. Duffy, Otis W. Brawley

    SECTION 6: CLINICAL TRIALS AND OUTCOMES ASSESSMENT

    35: Statistical Innovations in Cancer Research Don Berry
    36: Outcomes Assessment James A. Talcott

    PART III: PRINCIPLES OF CANCER DIAGNOSIS

    SECTION 7: CANCER PATHOLOGY

    37: Principles of Cancer Pathology Stan Hamilton

    SECTION 8: IMAGING

    38: Principles of Imaging Edward F. Patz, Jr.
    39: Interventional Radiology for the Cancer Patient Michael Wallace, Rony Avritscher

    PART IV: PRINCIPLES OF THERAPEUTIC MODALITIES

    SECTION 9: SURGICAL ONCOLOGY

    40: Principles of Surgical Oncology Raphael E. Pollock, Michael A. Choti, Donald L. Morton

    SECTION 10: RADIATION ONCOLOGY

    41: Principles of Radiation Oncology Joseph K. Salama, Mark W. Dewhirst, Ralph R. Weichselbaum

    SECTION 11: MEDICAL ONCOLOGY

    42: Principles of Medical Oncology William N. Hait, MD, ,PhD James F. Holland, MD, ScD (hc) Emil Frei III, MD Donald W. Kufe, MD Robert C. Bast Jr, MD Waun Ki Hong, MD

    SECTION 12: CHEMOTHERAPY

    43: Cytokinetics Larry Norton, Theresa Ann Gilewski
    44: Principles of Dose, Schedule, and Combination Chemotherapy Joseph P. Eder, William Hait
    45: Preclinical and Early Clinical Development of New Anticancer Agents Daniel D. Von Hoff, Axel Hanuske
    46: Pharmacology William Plunkett, Mark Ratain
    47: Drug Resistance and Its Clinical Circumvention Jeffrey Moscow, Erasmus Schneider, Branimir I. Sikic, Charles S. Morrow, Kenneth H. Cowan

    SECTION 13: CHEMOTHERAPEUTIC AGENTS

    48: Folate Antagonists Joseph R. Bertino, Barton A. Kamen, Peter D. Cole
    49: Pyrimidine and Purine Antimetabolites Giuseppe Pizzorno, Sunil Sharma, Yung-Chi Cheng
    50: Alkylating Agents and Platinum Antitumor Compounds Michael Colvin
    51: Drugs that Target DNA Topoisomerases William N. Hait, Eric H. Rubin
    52: Microtubule-Targeting Natural Products Eric Rowinsky

    SECTION 14: BIOTHERAPEUTICS

    53: InterferonsErnest C. Borden
    54: Cytokines and Hematopoietic Growth FactorsSuhendan Ekmekcioglu, Razelle Kurzrock, Elizabeth A. Grimm
    55: Monoclonal Serotherapy Robert C. Bast, Michael R. Zalutskym, Arthur E. Frankel, Robert J. Kreitman
    56: Vaccines and Immunostimulants Jeff Schlom, James L. Gulley, Philip M. Arlen, James W. Hodge

    SECTION 15: ENDOCRINE THERAPY

    57: Estrogens, Antiestrogens and Aromatase Inhibitors Aman U. Buzdar, Shaheenah Dawood, Harold A. Harvey, V. Craig Jordan
    58: Androgen Deprivation Strategies In The Treatment Of Advanced Prostate Cancer Samuel R. Denmeade

    SECTION 16: GENE THERAPY

    59: Cancer Gene Therapy Sunil J. Advani, Ralph R. Weichselbaum, Donald W. Kufe

    SECTION 17: BONE MARROW TRANSPLANTATION

    60: Hematopoietic Cell Transplantation Roy Jones, Elizabeth Shpall, Richard Champlin

    PART V: PRINCIPLES OF MULTIDISCIPLINARY MANAGEMENT

    SECTION 18: PSYCHO-ONCOLOGY

    61: Principles of Psycho-Oncology Jimmie C. Holland

    SECTION 19: CANCER REHABILITATION MEDICINE

    62: Principles of Cancer Rehabilitation Medicine Kristjan T. Ragnarsson

    SECTION 20: MULTIDISCIPLINARY MANAGEMENT

    63: Multidisciplinary Management James F. Holland, Emil Frei III, III, Waun Ki Hong, Donald W. Kufe, Robert C. Bast Jr, Raphael E. Pollock, Ralph R. Weichselbaum, William N. Hait
    64: Pregnancy and Cancer Jennifer K. Litton
    65: Cancer and Aging Arti Hurria, Hyman B. Muss, Harvey J. Cohen
    66: The Role of Integrative Oncology in Cancer Care Lorenzo Cohen, Nancy Russell, Kay Garcia, Moshe Frenkel

    SECTION 21: PAIN AND PALLIATION

    67: Palliative Care Diane Meier, Cardinale B. Smith, Gabrielle R. Goldberg
    68: Management of Cancer Pain Natalie Moryl, Alan Carver

    SECTION 22: CENTRAL NERVOUS SYSTEM

    69: Primary Neoplasms of the Central Nervous System in Adults Lisa M. DeAngelis
    70: Brain Metastases Lisa M. DeAngelis

    SECTION 23: THE EYE

    71: Neoplasms of the Eye Amy C. Schefler, David H. Abramsom, Ira J. Dunkel, Beryl McCormick

    SECTION 24: ENDOCRINE GLANDS

    72: Neoplasms of the Endocrine Glands: Pituitary Neoplasms Kalman D. Post
    73: Neoplasms of the Thyroid Steven I. Sherman
    74: Neoplasms of the Adrenal Cortex David E. Schteingart
    75: Neuroendocrine System and Gastroentero-pancreatic Endocrine System Evan Vosburgh

    SECTION 25: HEAD AND NECK

    76: Neoplasms of the Head and Neck Michael E. Kupferman, Erich M. Sturgis, David L. Schwartz, Adam Garden, Merrill S. Kies

    SECTION 26: THE THORAX

    77: Cancer of the Lung Charles Lu, Amir Onn, Ara A. Vaporciyan, Joe Y. Chang, Bonnie S. Glisson, Ritsuko Komaki, Ignacio I. Wistuba, Jack A. Roth, Roy S. Herbst
    78: Malignant Mesothelioma Harvey I. Pass, Michele Carbone, Hedy Kindler
    79: Thymomas and Thymic Tumors A. Philippe Chahinian
    80: Tumors of the Heart and Great Vessels Sarina van der Zee, A. Philippe Chahinian, Valentin Fuster
    81: Primary Germ Cell Tumors of the Thorax Anthony F. Greco, John D. Hainsworth

    SECTION 27: GASTROINTESTINAL TRACT

    82: Neoplasms of the Esophagus Stephen G. Swisher, David C. Rice, Jaffer A. Ajani, Ritsuko K. Komaki, Mark K. Ferguson
    83: Carcinoma of the Stomach Paul Mansfield, James Yao, Christopher Crane, Takeshi Sano
    84A: Treatment of Liver Metastases Nancy E. Kemeny, Micheal DAngelica
    84B: Kemeny Treatment of Liver Metastases Max W. Sung, Swan N. Thung
    85: Gallbladder and Bile Duct Cancer Ahmed O. Kaseb, Steven A. Curley, Melanie Thomas
    86: Neoplasms of the Exocrine Pancreas Robert A. Wolff, Christopher H. Crane, Donghui Li, Douglas B. Evans
    87: Neoplasms of the Small Intestine, Vermiform Appendix, Peritoneum and Carcinoma of the Colon and Rectum James C. Padussis, Georgia M. Beasley, Nicole McMahon, Douglas S. Tyler, Kirk Ludwig
    88: Neoplasms of the Anus Bruce Minsky

    SECTION 28: GENITOURINARY TRACT

    89: Renal Cell Carcinoma Derek Raghavan, Brian I. Rini, Daniel Y.C. Heng, Ming Zhou, Andrew Novick
    90: Tumors Of The Renal Pelvis And Ureter Derek Raghavan, Ali-Reza Golshayan, Inderbir Gill, Cristina Magi-Galluzzi
    91: Bladder Cancer Derek Raghavan,John Stein, Richard Cote, J. Stephen Jones
    92: Neoplasms of the Prostate Christopher Logothetis
    93: Tumors of the Penis and Urethra Donald F. Lynch
    94: Testis Cancer Christian Kollmansberger, Siamak Daneshmand, Eric Hansen, Christopher L. Corless, Bruce J. Roth, Craig R. Nichols

    SECTION 29: FEMALE REPRODUCTIVE ORGANS

    95: Neoplasms of the Vulva and Vagina Jacob Rotmensch
    96: Neoplasms of the Cervix Anuja Jhingran
    97: Endometrial Cancer Carmel J. Cohen, Jamal Rahaman
    98: Neoplasms of the Fallopian Tube Carmel J. Cohen, Jamal Rahaman
    99: Ovarian Cancer Jonathan S. Berek, Robert Bast, Michael L. Friedlander
    100: Molar Pregnancy and Gestational Trophoblastic Neoplasia Ross S. Berkowitz, Donald Goldstein
    101: Gynecologic Sarcomas Carmel J. Cohen, Jamal Rahaman

    SECTION 30: THE BREAST

    102: Neoplasms of the Breast Gabriel N. Hortobagyi, Laura Esserman, Thomas A. Buchholz

    SECTION 31: THE SKIN

    103: Melanoma Patrick Hwu, Jeff Gershenwald, Boris Bastian
    104: Other Skin Cancers Arthur Sober, Victor A. Neel

    SECTION 32: BONE AND SOFT TISSUE

    105: Bone Tumors Tim Damron
    106: Soft Tissue Sarcomas Peter Pisters , Brian OSullivan, Robert G. Maki

    SECTION 33: HEMATOPOIETIC SYSTEM

    107: The Myelodyplastic Syndrome Lewis R. Silverman
    108: Acute Myeloid Leukemia and Other Mast Cell Neoplasms Charles A. Schiffer, Richard M. Stone
    109: Chronic Myeloid Leukemia Magop M. Kantarjian, Jorge Cortes
    110: Acute Lymphocytic Leukemia Stefan Faderl, Ching-Hon Pui, Susan OBrien, Hagop M. Kantarjian
    111: Chronic Lymphocytic Leukemia Kanti Rai, Matthew Kaufman
    112: Hodgkin Disease James OArmitage, Peter M. Mauch, Lawrence Weiss
    113: Non-Hodgkin Lymphoma Arnold S. Freedman
    114: Mycosis Fungoides and the Sezary Syndrome Richard T. Hoppe, Youn H. Kim, Ranjana Advani
    115: Plasma Cell Tumors Kenneth C. Anderson, Teru Hideshima, Noopur Raje
    116: Myeloproliferative Neoplasms: Essential Thrombocythemia, Primary Myelofibrosis and Polycythemia Vera Ayalew Tefferi

    SECTION 34: NEOPLASMS IN AIDS

    117: Neoplasms in Acquired Immunodeficiency Syndrome David T. Scadden, Jeremy S. Abramson

    SECTION 35: UNKNOWN PRIMARY SITE

    118: Neoplasms of Unknown Primary Site John D. Hainsworth, F. Anthony Greco

    SECTION 36: PEDIATRIC ONCOLOGY

    119: Principles of Pediatric Oncology Maura OLeary, Greg Reaman

    SECTION 37: COMPLICATIONS OF CANCER AND THEIR TREATMENT

    120: Cancer Anorexia and Cachexia Takao Ohnuma
    121: Antiemetic Therapy David Ettinger, Aditya Bardia
    122: Neurologic Complications Lisa M. DeAngelis
    123: Dermatologic Complications of Cancer Chemotherapy Cindy Berthelot, Joy H. Kunishige, Narin Apisarnthanarax, Madeleine M. Duvic
    124: Skeletal Complications Samuel Kenan, Jeff Mechanick, Michael Via
    125: Hematologic Complications and Blood Bank Support Kenneth C. Anderson, Richard M. Kaufman
    126: Coagulopathic Complications of Cancer Patients Jacob H. Rand, Maria DeSancho
    127: Urologic Complications Christopher J. Logothetis, Diana M. Hey
    128: Cardiac Complications Michael S. Ewer, Steven M. Ewer, Thomas Suter
    129: Respiratory Complications Vickie R. Shannon, George A. Eapen, Carlos A. Jimenez, Rodolfo C. Morice, Elizabeth L. Travis,
    Lara Bashoura, Amar Safdar, Scott E. Evans, Roberto Adachi, Saadia A. Faiz, Diwakar D. Balachandran, Joseph L. Nates, S. Egbert Pravinkumar, Burton F. Dickey
    130: Gastrointestinal and Hepatic Complications in Cancer Patients Robert Bresalier, Marta L. Davila
    131: Oral Complications of Cancer and Their Treatment Stephen T. Sonis
    132: Gonadal Complications Catherine E. Klein, Peter Kabos
    133: Endocrine Complications and Paraneoplastic Syndromes Robert F. Gagel, Sai-Ching, Jim Yeung
    134: Treatment -Related Secondary Cancers Susan R. Rheingold, Alfred I. Neugut, Thomas Uldrick, Anna T. Meadows

    SECTION 38: INFECTION IN THE CANCER PATIENT

    135: Infections in Patients with Cancer Kenneth V.I. Rolston, Gerald P. Bodey

    SECTION 39: ONCOLOGIC EMERGENCIES

    136: Oncologic Emergencies S. Jim Yeung, Carmen Escalante

    SECTION 40: ONCOLOGY AND INFORMATICS

    137: Oncology Informatics Edward P. Ambinder

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