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Vascular Disease, Alzheimer's Disease, and Mild Cognitive Impairment
Advancing an Integrated Approach
9780190634230
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Description
Alzheimers disease (AD) and vascular dementia (VaD) are commonly viewed as the first and second most common types of dementia, respectively. The traditional paradigm has been to view and treat each illness as a separate entity with a separate pathophysiology. However, clinical and pathological studies suggest that the boundary separating AD and VaD, as well as their mild cognitive impairment (MCI) analogs, is not well defined. Thus, there is increased interest in viewing thesediseases along a spectrum because of the significant overlap in the characterization and diagnosis of AD, VaD, and MCI. The focus of this edited volume is to examine how AD and VaD, as well as their MCI analogs, are best viewed as a heterogeneous, intersecting, if not a continuous disease state ratherthan separate, distinct entities. This book examines this approach by providing empirically based evidence, reviews of the literature, and chapters by key leaders in the field and will be of interest to clinical neuropsychologists and anyone studying or treating dementia in its many forms.
Product Details
88528
9780190634230
9780190634230
Data sheet
- Publication date
- 2020
- Issue number
- 1
- Cover
- hard cover
- Pages count
- 504
- Dimensions (mm)
- 156 x 235
- Weight (g)
- 839
- Preface; Part 1: Epidemiology and Neuropsychology; Chapter 1: Vascular risk factors and their relationship to brain aging: Findings from the Framingham Heart Study; Chapter 2: Neuropsychological Profiles in Alzheimers/ Vascular Spectrum Dementia; Chapter 3: Neuropsychological Diagnostic Criteria for Mild Cognitive Impairment due to Alzheimers Disease; Chapter 4: Vascular Cognitive Impairment; Chapter 5: Decline in Everyday Functioning in MCI and Dementia: A Neuropsychological Perspective; Chapter 6: Heterogeneity in Dementia and MCI: Using Statistical Modeling Techniques; Chapter 7: Apraxic and Action-Intentional Disorders Associated With Vascular And Degenerative Dementing Diseases; Part 2: Neuroimaging; Chapter 8: Cerebral small vessel disease and the risk of dementia and cognition decline; Chapter 9: Structural MRI in Alzheimers disease: Are we measuring the right stuff; Chapter 10: Advances in Multi-Modal Imaging Across the Spectrum of Normal to Pathological aging: Incorporating Vascular Comorbidities Common to Alzheimers disease and Vascular Dementia; Part 3: Blood-Brain-Barrier and Cardiogenic Mechanisms; Chapter 11: The Blood-Brain Barrier in Cognitive Decline and Alzheimers Disease; Chapter 12: Arterial Stiffening and Cerebrovascular Resistance in Cognitive Decline and Alzheimers Disease; Chapter 13: Hemodynamics in Alzheimers Disease and Vascular Cognitive Impairment & Dementia; Part 4: Neuropathological and Neurophysiological Mechanisms; Chapter 14: Neuropathology of AD/ VaD Dementia; Chapter 15: Potential of blood- and CSF-based biomarkers for AD diagnostics; Chapter 16: Unravelling the Role of Mitochondria in Alzheimers disease: Toward Assembling the Puzzle; Part 5: Treatment and Intervention; Chapter 17: Dementia and Elective Surgeries: Considerations for Neuropsychologists; Chapter 18: Management of Mild Cognitive Impairment;
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